Medical research

Researchers reformulate the model of mitochondrial function

The discovery confirms the model proposed by the team in 2008 to account for observations that could not be explained by the established model of mitochondrial function. Mitochondria are the organelles in the interior of ...

Medical research

When DNA is out of place

When DNA that turns up in the wrong place in mammalian cells, the innate immune system reacts by secreting interferons. The structure and mode of action of the enzyme that mediates this response have now been elucidated.

Parkinson's & Movement disorders

How disease mutations affect the Parkin protein

Researchers at the MRC Laboratory of Molecular Biology in the United Kingdom have determined the crystal structure of Parkin, a protein found in cells that when mutated can lead to a hereditary form of Parkinson's disease. ...

Genetics

Tiny worm sheds light on giant mystery about neurons

Scientists have identified a gene that keeps our nerve fibers from clogging up. Researchers in Ken Miller's laboratory at the Oklahoma Medical Research Foundation (OMRF) found that the unc-16 gene of the roundworm Caenorhabditis ...

Neuroscience

See-through 'MitoFish' opens a new window on brain diseases

German scientists have demonstrated a new way to investigate mechanisms at work in Alzheimer's and other neurodegenerative diseases, which also could prove useful in the search for effective drugs. For new insights, they ...

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