New cancer driver found: Monoclonal antibody therapy stops tumor growth in mice
(Medical Xpress)—Approximately 90 percent of cancers start within tissues that form the inner linings of various organs. Decades of accumulated genetic mutations can, on occasion, induce cells specialized ...
Cancer
May 08, 2013 |
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Wip1 could be new target for cancer treatment
Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new ...
Cancer
May 06, 2013 |
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Team finds markers related to ovarian cancer survival and recurrence
(Medical Xpress)—Researchers at the University of Illinois have identified biomarkers that can be used to determine ovarian cancer survival and recurrence, and have shown how these biomarkers interact with ...
Cancer
Apr 30, 2013 |
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Chemoresponse assay helps boost ovarian cancer survival
This spring, a team of researchers has released results from an eight-year study that shows improved survival rates for women diagnosed with ovarian cancer who undergo cancer tumor testing to determine the best treatment.
Cancer
Apr 25, 2013 |
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New approaches to maximize the antitumor activity of interferon
Interferons have antitumor activity and have been used to treat a variety of malignancies, including colorectal and ovarian cancers. However, their effectiveness varies. A clearer understanding of the role ...
Medical research
Apr 16, 2013 |
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Resistance is futile: Researchers identify gene that mediates cisplatin resistance in ovarian cancer
Platinum compounds, such as cisplatin and carboplatin, induce DNA cross-linking, prohibiting DNA synthesis and repair in rapidly dividing cells. They are first line therapeutics in the treatment of many solid tumors, but ...
Cancer
Apr 15, 2013 |
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Two-step ovarian cancer immunotherapy made from patients' own tumor shows promise
As many as three quarters of advanced ovarian cancer patients appeared to respond to a new two-step immunotherapy approach—including one patient who achieved complete remission—according research from the Perelman School ...
Cancer
Apr 06, 2013 |
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Nanotech'ed RNA drug reduces ovarian cancer tumors by 83 percent
By loading fragile RNA into silicon nanoparticles, researchers from The Methodist Hospital and two other institutions found a new drug delivery system can reduce the size of ovarian tumors by as much as 83 ...
Cancer
Feb 14, 2013 |
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Study drug is first to help patients with recurrent low-grade ovarian cancer
Low-grade serous ovarian cancer is less common and aggressive than the high-grade variety, yet exceptionally difficult to treat when frontline therapy fails.
Cancer
Feb 08, 2013 |
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Engineered oncolytic herpes virus inhibits ovarian and breast cancer metastases
A genetically reprogrammed Herpes simplex virus (HSV) can cure metastatic diffusion of human cancer cells in the abdomen of laboratory mice, according to a new study published January 31 in the Open Access journal PLOS Pa ...
Cancer
Jan 31, 2013 |
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Two-step immunotherapy attacks advanced ovarian cancer
Most ovarian cancer patients are diagnosed with late stage disease that is unresponsive to existing therapies. In a new study, researchers from the Perelman School of Medicine at the University of Pennsylvania School of Medicine ...
Cancer
Jan 31, 2013 |
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Preclinical study identifies 'master' proto-oncogene that regulates ovarian cancer metastasis
Scientists at The University of Texas MD Anderson Cancer Center have discovered the signaling pathway whereby a master regulator of cancer cell proteins – known as Src – leads to ovarian cancer progression when exposed ...
Cancer
Jan 29, 2013 |
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DNA-repairing protein may be key to preventing recurrence of some cancers
Just as the body can become resistant to antibiotics, certain methods of killing cancer tumors can end up creating resistant tumor cells. But a University of Central Florida professor has found a protein ...
Cancer
Jan 28, 2013 |
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Team finds mechanism of one of the most powerful tumor-suppressor proteins, Chd5
A team of cancer researchers at Cold Spring Harbor Laboratory (CSHL) has solved the mystery of how one of the most powerful of the body's natural tumor-suppressing proteins, called Chd5, exerts its beneficial effects.
Cancer
Jan 10, 2013 |
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Ovarian cancer stem cell study puts targeted therapies within reach
Researchers at Yale School of Medicine have identified a key link between stem cell factors that fuel ovarian cancer's growth and patient prognosis. The study, which paves the way for developing novel targeted ovarian cancer ...
Cancer
Jan 07, 2013 |
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