Cutting calories might help you live longer, but not without increased physical activity
Dietary restriction can slow age-related diseases and extend the lifespan of all species tested to date. Understanding this phenomenon might help people live longer, preferably without having to drastically limit calories. ...
Medical research
Jul 03, 2012 |
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Lack of oxygen in cancer cells leads to growth and metastasis
(Medical Xpress)—It seems as if a tumor deprived of oxygen would shrink. However, numerous studies have shown that tumor hypoxia, in which portions of the tumor have significantly low oxygen concentrations, ...
Cancer
Sep 13, 2012 |
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Novel herbal compound offers potential to prevent and treat Alzheimer's disease
Administration of the active compound tetrahydroxystilbene glucoside (TSG) derived from the Chinese herbal medicine Polygonum multiflorum Thunb, reversed both overexpression of α-synuclein, a small protein found in the brain, ...
Alzheimer's disease & dementia
Feb 16, 2013 |
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Breaking oncogene's hold on cancer cell provides new treatment direction
Just as people's bodies and minds can become addicted to substances such as drugs, caffeine, alcohol, their cancers can become addicted to certain genes that insure their continued growth and dominance.
Cancer
Dec 08, 2011 |
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Studies help clarify the role of lapatinib and trastuzumab in treating HER2 positive breast cancer
In patients with HER2-positive breast cancer, Tykerb (lapatinib) has been used both in combination with herceptin (trastuzumab) and as an alternative single-agent therapy for pre-surgery (neo-adjuvant) chemotherapy treatment. ...
Cancer
Jan 16, 2012 |
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Cell surface transporters exploited for cancer drug delivery
Whitehead Institute scientists report that certain molecules present in high concentrations on the surfaces of many cancer cells could be exploited to funnel lethal toxic molecules into the malignant cells. In such an approach, ...
Genetics
Dec 02, 2012 |
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Researchers uncover previously unknown mechanism of memory formation
(Medical Xpress)—It takes a lot to make a memory. New proteins have to be synthesized, neuron structures altered. While some of these memory-building mechanisms are known, many are not. Some recent studies have indicated ...
Neuroscience
Jan 30, 2013 |
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Study finds two genes affect anxiety, behavior in mice with too much MeCP2
The anxiety and behavioral issues associated with excess MeCP2 protein result from overexpression of two genes (Crh [corticotropin-releasing hormone] and Oprm 1 [mu-opioid receptor MOR 1]), which may point the way to treating ...
Genetics
Jan 08, 2012 |
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Sodium transporter appears likely target for treating salt-sensitive hypertension
Genetics and demographics likely put you at risk for salt-sensitive hypertension, and scientists are looking for a way to protect you.
Medical research
Feb 26, 2013 |
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UK study provides insight into cancer progression
The University of Kentucky has announced that Dr. Daret St. Clair, the James Graham Brown Endowed Chair and professor of toxicology, has published the first comprehensive study that provides insight into the relationship ...
Cancer
Feb 22, 2012 |
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Researchers identify new regulator in allergic diseases
Researchers have taken a critical step in understanding how allergic reactions occur after identifying a genetic signature for regulation of a key immune hormone, interleukin (IL-13).
Immunology
Mar 28, 2012 |
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A boost in microRNA may protect against sepsis and other inflammatory diseases
Acute inflammatory diseases, such as sepsis, as well as chronic inflammatory diseases like diabetes and arthritis, develop as a result of sustained inflammation of the blood vessel wall. Researchers at Brigham and Women's ...
Inflammatory disorders
May 24, 2012 |
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A 'Kit' for increasing insulin production
Scientists from Western University in London, Canada and the Children's Health Research Institute, an Institute within the Lawson Health Research Institute, have identified the critical role of a receptor ...
Diabetes
Jul 17, 2012 |
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