News tagged with p53 mutations

'Achilles heel' of pancreatic cancer identified

A research team at Georgetown Lombardi Comprehensive Cancer Center reports that inhibiting a single protein completely shuts down growth of pancreatic cancer, a highly lethal disease with no effective therapy.

May 01, 2014
popularity 4.9 / 5 (15) | comments 0

Wip1 could be new target for cancer treatment

Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new ...

May 06, 2013
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Prions and cancer: A story unfolding

Prions, the causal agents of Mad Cow and other diseases, are very unique infectious particles. They are proteins in which the complex molecular three-dimensional folding process just went astray. For reasons not yet understood, ...

Jun 25, 2012
popularity 5 / 5 (1) | comments 0

Gene found to play role in early cancer

(Medical Xpress) -- Mutations to a gene called p53 have been linked to half of all cancers, leading to tumor growth and the spread of cancerous cells. Now, a Cornell-led study identifies for the first time the mechanisms ...

Aug 24, 2011
popularity 5 / 5 (2) | comments 0 | with audio podcast

Cancer cells and stem cells share same origin: study

Oncogenes are generally thought to be genes that, when mutated, change healthy cells into cancerous tumor cells. Scientists at the Keck School of Medicine of the University of Southern California (USC) have proven that those ...

Jul 18, 2011
popularity 5 / 5 (4) | comments 1 | with audio podcast