News tagged with p53 pathway

Deficiency in p53 anti-tumor protein delays DNA repair after radiation

Researchers at Moffitt Cancer Center have found that a deficiency in an important anti-tumor protein, p53, can slow or delay DNA repair after radiation treatment. They suggest that this is because p53 regulates the expression ...

Cancer Apr 23, 2013 | 4 / 5 (1) | 0 |

Cancer cell metabolism kills

Adenosine-5'-triphosphate (ATP) is the main energy source for all forms of work inside our cells. Scientists from the University of Helsinki, Finland, have found that even a short-term shortage of ATP supply ...

Cancer Apr 15, 2013 | 5 / 5 (7) | 0 |

Cancer suppressor gene links metabolism with cellular aging

The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...

Cancer Jan 13, 2013 | 3.7 / 5 (3) | 0 |

At last, a reason why stress causes DNA damage

For years, researchers have published papers that associate chronic stress with chromosomal damage.

Medical research Aug 21, 2011 | 5 / 5 (13) | 7 |