Tulane University researchers have discovered that the protein PHLDB3, thought to be a potential tumor suppressor, actually allows cancer cells to thrive in pancreatic, prostate, colon, breast, lung, and other common cancers. ...
Jan 24, 2017
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A new study by University of Kentucky Markey Cancer Center researchers shows that chloroquine – a drug currently used to treat malaria – may be useful in treating patients with metastatic cancers.
Jan 11, 2017
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Tumor suppressors stop healthy cells from becoming cancerous. Researchers from Charité - Universitätsmedizin Berlin, the Medical University of Graz and the German Institute of Human Nutrition in Potsdam-Rehbruecke have ...
Dec 21, 2016
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Discovered in the 1970s, tumor suppressors are among the most important proteins in the body. A master regulator of growth—"the guardian of the genome"—the p53 protein monitors cell growth for errors. We rely on suppressors ...
Dec 8, 2016
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Individuals with Li-Fraumeni syndrome are at an increased risk for a number of cancers, including breast and bone cancer. Li-Fraumeni syndrome is an inherited cancer disorder caused by mutations in the tumor suppressing protein ...
Nov 21, 2016
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Could limiting food intake be a valid treatment strategy for certain types of cancers? New research in The FASEB Journal suggests "maybe." In a report appearing online in The FASEB Journal, scientists show that food restriction ...
Nov 16, 2016
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Using microsecond timescale molecular dynamics simulations, a new study published in Scientific Reports reveals p53 weak spots and sheds light on the protein instability, which is linked to its tendency to aggregate and form ...
Sep 7, 2016
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Research has shown that the growth of cancerous tumours is affected by transforming growth factor (TGFβ) in the body's cells; TGFβ both suppresses and stimulates tumour development. But it has not been understood how this ...
Aug 23, 2016
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Proteins that bind DNA or RNA are usually put in different categories, but researchers at Umeå University in Sweden and Inserm in France recently showed how the p53 protein has the capacity to bind both and how this controls ...
Aug 4, 2016
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A drug that can kill cancer cells while leaving normal cells unharmed may be within our grasp thanks to research from A*STAR, although the approach is still several years away from clinical trials.
Jul 27, 2016
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