CHARGE, which affects 1 in 10,000 babies, is an acronym whose letters stand for some of the more common symptoms of the condition: coloboma of the eye, heart defects, atresia of the choanae, retardation of growth and/or development, ...
Aug 3, 2014
0
0
For years, researchers have published papers that associate chronic stress with chromosomal damage.
Aug 21, 2011
7
0
The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...
Jan 13, 2013
0
0
Infections due to the sexually transmitted bacterium Chlamydia trachomatis often remain unnoticed. The pathogen is not only a common cause of female infertility; it is also suspected of increasing the risk of abdominal cancer. ...
Nov 14, 2014
0
0
Scientists from Trinity College Dublin have identified a novel target that could help to identify 'cancer stem cells' while they are in their inactive state. The scientists could then jolt these cells into action so that ...
Nov 27, 2015
0
164
Researchers at UCLA have found that a protein that serves as a suppressor of cancer diminishes in skin and mouth epithelial cells as the human body ages.
Jul 16, 2015
0
2608
Scientists have long known that the protein p53, when mutated, is a critical factor in the onset of many different kinds of cancer. In its unmutated form, however, it is known to protect against cancer.
Mar 18, 2019
0
449
A team of researchers with affiliations to a number of research centers in the U.S. has found that the protein p53 serves as a controlling mechanism for apoptotic (naturally dying) cells through the immunoglobulin Death Domain ...
A metabolic pathway that is up-regulated in certain breast cancers promotes the disease's progression by activating a cell signaling protein called Arf6, according to a paper published in the Journal of Cell Biology. The ...
Apr 6, 2016
0
24
Aggressive cancer growth and alterations in gene activity without changes in DNA sequence (epigenetics) are associated with mutant p53 proteins, according to new research from the Perelman School of Medicine at the University ...
Sep 2, 2015
1
139
