One in six people with broken heart syndrome had cancer and they were less likely to survive for five years after it occurred, according to new international research in Journal of the American Heart Association.
Jul 17, 2019
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Opioids are not among the most effective—or longest lasting—options available for relief from acute dental pain, a new examination of the results from more than 460 published studies has found.
Apr 17, 2018
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Tulane University researchers have discovered a possible genetic cause for hypermobility (commonly known as double-jointedness) and a range of associated connective tissue disorders such as hypermobile Ehlers-Danlos syndrome, ...
Apr 10, 2023
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Spine-related pain is increasingly common in older adults. While medications play an important role in pain management, their use has limitations in geriatric patients due to reduced liver and kidney function, comorbid medical ...
Jun 28, 2022
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Researchers at Karolinska Institutet in Sweden have discovered a new sensory organ that is able to detect painful mechanical damage, such as pricks and impacts. The discovery is being published in the journal Science.
Aug 15, 2019
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Common antidepressants interact with the opioid pain medication tramadol to make it less effective for pain relief, according to a study from University Hospitals (UH). These findings have important implications for the opioid ...
Jun 26, 2019
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Dear Mayo Clinic: My tailbone has been hurting for the past few weeks. I have read that it takes a while to heal, but is there anything I can do in the meantime to lessen the pain? At what point would it be necessary to see ...
Aug 13, 2019
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Knee replacement surgery is increasingly common among people over 80 sidelined with knee pain, and the procedure isn't as hazardous for them as often assumed.
Mar 22, 2022
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A United States Food and Drug Administration mandate to limit the dosage of acetaminophen in pills that combine acetaminophen and opioid medications is significantly associated with subsequent reductions in serious liver ...
Mar 7, 2023
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(Medical Xpress)—The first indication that you're sick is typically one or more symptoms: perhaps a cough, fever, abdominal pain, etc. Symptoms are high-level clinical manifestations of a disease that, at a lower level, ...
An analgesic (also known as a painkiller) is any member of the diverse group of drugs used to relieve pain (achieve analgesia). The word analgesic derives from Greek an- ("without") and algos ("pain"). Analgesic drugs act in various ways on the peripheral and central nervous systems; they include paracetamol (acetaminophen), the non-steroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, narcotic drugs such as morphine, synthetic drugs with narcotic properties such as tramadol, and various others.
In choosing analgesics, the severity and response to other medication determines the choice of agent; the WHO pain ladder, originally developed in cancer-related pain, is widely applied to find suitable drugs in a stepwise manner. The analgesic choice is also determined by the type of pain: for neuropathic pain, traditional analgesics are less effective, and there is often benefit from classes of drugs that are not normally considered analgesics, such as tricyclic antidepressants and anticonvulsants.
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