Opioid receptors are proteins in the central nervous system that are targeted by opioid drugs for pain relief. There are three subtypes of opioid receptors, MOP, DOP and KOP, in addition to the opioid-related NOP receptor.
A research team with members from Monash University, the ARC Centre for Cryo-electron Microscopy of Membrane Proteins, the University of Tokyo and the University of Otago have determined the shape and kinetics of an important ...
A team of researchers from Université Paris-Saclay and Université Paris Descartes has developed a nano-drug that has been found to reduce pain in rodents. In their paper published in the journal Science Advances, the group ...
With the support of the National Institute on Drug Abuse, scientists at Wake Forest School of Medicine have been working to find a safe, non-addictive pain killer to help fight the current opioid crisis in this country.
Aug 29, 2018
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A newly identified protein can be manipulated to make opioid painkillers effective at lower doses while also muting the reward mechanism that leads to addiction, Mount Sinai researchers have found.
Feb 12, 2018
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A brain region controlling whether we feel happy or sad, as well as addiction, is remodeled by chronic pain, reports a new Northwestern Medicine study.
Dec 21, 2015
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Despite the abuse potential of opioid drugs, they have long been the best option for patients suffering from severe pain. The drugs interact with receptors on brain cells to tamp down the body's pain response. But now, neuroscientists ...
Apr 30, 2015
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(Medical Xpress)—A team of researchers at Stanford University has found a way to turn the perception of pain on and off using only a light source. In their paper published in the journal Nature Biotechnology, the team describes ...
A new study of itch adds to growing evidence that the chemical signals that make us want to scratch are the same signals that make us wince in pain.
May 2, 2011
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Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems—prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same pain relief, and paradoxically, ...
Apr 9, 2024
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