Psychology & Psychiatry
Friends 'better than morphine': Larger social networks release more pain-killing endorphin
People with more friends have higher pain tolerance, Oxford University researchers have found.
Apr 28, 2016
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News tagged with pain tolerance
Medications
Morphine tolerance found to result from Tiam1-mediated maladaptive plasticity in spinal neurons
Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems—prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same pain relief, and paradoxically, ...
Apr 9, 2024
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Health
Physical activity linked to higher pain tolerance
A new analysis of data from more than 10,000 adults shows that people who were physically active had higher pain tolerance than those who were sedentary, and that those with a higher level of activity had a higher level of ...
May 24, 2023
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Health
Link found between pain sensitivity and circadian rhythm
A team of researchers with members from Université Claude Bernard Lyon, Hospices Civils de Lyon and Paris-Saclay Université has found a link between pain sensitivity and a person's circadian rhythm. In their paper published ...
Genetics
Study: Opioid drug tolerance develops from interplay of key gene and cholesterol
UF Scripps Biomedical Research scientists have a discovered a key gene that is shedding light on how people develop tolerance to pain-relievers over time, a problem that raises risk of addiction and overdose.
Aug 18, 2022
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Genetics
With gene therapy, scientists develop opioid-free solution for chronic pain
A gene therapy for chronic pain could offer a safer, non-addictive alternative to opioids. Researchers at the University of California San Diego developed the new therapy, which works by temporarily repressing a gene involved ...
Mar 10, 2021
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Psychology & Psychiatry
Why do more men than women commit suicide?
Why do more men die when they attempt suicide than women? The answer could lie in four traits, finds scientists.
Sep 26, 2016
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Medications
New drug target could prevent tolerance and addiction to opioids, neuroscience study finds
Researchers have identified a brain mechanism that could be a drug target to help prevent tolerance and addiction to opioid pain medication, such as morphine, according to a study by Georgia State University and Emory University.
Aug 22, 2016
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Neuroscience
Study shows why some pain drugs become less effective over time
Researchers at the University of Montreal's Sainte-Justine Hospital have identified how neural cells like those in our bodies are able to build up resistance to opioid pain drugs within hours. Humans have known about the ...
Apr 3, 2012
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Medications
Reformulated imatinib eliminates morphine tolerance in lab studies
By reformulating the common cancer drug imatinib (Gleevec), researchers have eliminated morphine tolerance in rats – an important step toward improving the effectiveness of chronic pain management in patients, according ...
Feb 21, 2012
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