Diseases, Conditions, Syndromes

Genomic methods aid study of Seattle 2017-2022 Shigella outbreak

A genomic study of a sustained, multidrug-resistant Shigellosis outbreak in Seattle enabled scientists to retrace its origin and spread. Additional analysis of the gut pathogen and its transmission patterns helped direct ...

Diseases, Conditions, Syndromes

New tool enables easy, effective disease tracking

A new open source, cloud-based tool called IDseq can rapidly detect, identify and track emerging pathogens such as SARS-CoV-2. It can identify pathogens before there is an available complete genome sequence, and can therefore ...

Genetics

PopPUNK advances speed of bacterial pathogen surveillance

Differences in genetic diversity among bacterial pathogens correlate with clinically important factors, such as virulence and antimicrobial resistance, prompting the need to identify clusters of similar bacterial strains. ...

Genetics

What role do genome variations play in tuberculosis?

Tuberculosis is caused by Mycobacterium tuberculosis. In 2016, this was the most common causative pathogen for death by infectious diseases. Therefore, investigating the biology of infection and disease development is important ...

Genetics

New technique searches 'dark genome' for disease mutations

When doctors can't find a diagnosis for patient's disease, they turn to genetic detectives. Equipped with genomic sequencing technologies available for less than 10 years, these sleuths now routinely search through a patient's ...

Genetics

New technology traces resistance gene quickly

A new resistance gene has been found in coli bacteria among pigs, broiler meat and humans in China. Bacteria with the same resistance gene have now also been found in Denmark, according to a new Danish study. The National ...

Genetics

Real-time genome sequencing helps control hospital outbreak

Pioneering use of whole genome sequencing in real time to help control a hospital outbreak is reported in an article published in the open access journal Genome Medicine. The research corroborates the use of the technique ...

Genetics

Genome sequencing of MRSA infection predicts disease severity

The spread of the antibiotic-resistant pathogen MRSA (methicillin-resistant Staphylococcus aureus) remains a concerning public health problem, especially among doctors trying to determine appropriate treatment options for ...

Diseases, Conditions, Syndromes

Tuberculosis genomes portray secrets of pathogen's success

By any measure, tuberculosis (TB) is a wildly successful pathogen. It infects as many as two billion people in every corner of the world, with a new infection of a human host estimated to occur every second.

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