News tagged with pathogenesis
New findings contradict dominant theory in Alzheimer's disease
For decades the amyloid hypothesis has dominated the research field in Alzheimer's disease. The theory describes how an increase in secreted beta-amyloid peptides leads to the formation of plaques, toxic clusters of damaged ...
Neuroscience
Oct 28, 2011 |
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Scientists discover cinnamon compounds' potential ability to prevent Alzheimer's
Cinnamon: Can the red-brown spice with the unmistakable fragrance and variety of uses offer an important benefit? The common baking spice might hold the key to delaying the onset of –– or warding off ...
Alzheimer's disease & dementia
May 23, 2013 |
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Scientists use nature against nature to develop an antibiotic with reduced resistance
A new broad range antibiotic, developed jointly by scientists at The Rockefeller University and Astex Pharmaceuticals, has been found to kill a wide range of bacteria, including drug-resistant Staphylococcus (MRSA) bacter ...
Medications
Apr 10, 2013 |
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Transcriptional barcoding of retinal cells identifies disease target cells
(Medical Xpress) -- By developing a large scale gene expression map for retinal cell types, FMI Neurobiologists have been able to identify the cells in the retina, where the genes causing retinal diseases ...
Neuroscience
Jan 23, 2012 |
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New research discovery provides therapeutic target for ALS
Research led by Dr. Udai Pandey, Assistant Professor of Genetics at LSU Health Sciences Center New Orleans, has found that the ability of a protein made by a gene called FUS to bind to RNA is essential to the development ...
Genetics
Dec 19, 2012 |
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Researchers trick bacteria to deliver a safer vaccine
(Medical Xpress)—Vaccines that employ weakened but live pathogens to trigger immune responses have inherent safety issues but Yale researchers have developed a new trick to circumvent the problem—using ...
Medical research
Mar 13, 2013 |
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New structural insight into neurodegenerative disease
A research team from the Korea Advanced Institute of Science and Technology (KAIST) released their results on the structure and molecular details of the neurodegenerative disease-associated protein Ataxin-1. ...
Genetics
Mar 14, 2013 |
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A mutation in a protein-sorting gene is linked with Parkinson's disease
Parkinson disease (PD) is a devastating incurable disease in which degeneration of dopamine neurons in the brainstem leads to tremors and problems with movement and coordination. An increasing proportion of patients appear ...
Genetics
Jul 14, 2011 |
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Promising target in treating and preventing the progression of heart failure identified
Researchers at Mount Sinai School of Medicine have identified a new drug target that may treat and/or prevent heart failure. The team evaluated failing human and pig hearts and discovered that SUMO1, a so-called "chaperone" ...
Cardiology
Sep 07, 2011 |
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Child food allergy prevalence linked to urban/rural status
(HealthDay) -- The prevalence of childhood food allergy is associated with urban/rural status, even after adjusting for confounding variables, according to a study published online May 17 in Clinical Pediatrics.
Pediatrics
Jun 15, 2012 |
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Scientists identify likely predictors of hepatitis C severity: viral evolution and host protein levels
(Medical Xpress) -- Scientists at the National Institutes of Health have identified several factors in people infected with the hepatitis C virus that may predict whether the unusually rapid progression of disease from initial ...
Diseases, Conditions, Syndromes
Jul 23, 2012 |
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Finding the origins of infant leukaemia
Leukaemia arises as a result of genetic or epigenetic alterations in blood cells, leading to an aberrant accumulation of undifferentiated blasts. Understanding the molecular pathogenesis and aetiology of ...
Cancer
Oct 15, 2012 |
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Providing brain cells with the 3rd dimension to grow outside the body
Researchers at Sahlgrenska Academy in collaboration with Chalmers University of Technology developed a unique Bioactive3D culture system for brain cells. This system gives new possibilities to study cell-cell ...
Medical research
Jan 25, 2013 |
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Modeling Alzheimer's disease using iPSCs
Working with a group from Nagasaki University, a research group at the Center for iPS Cell Research and Application (CiRA) at Japan's Kyoto University has announced in the Feb. 21 online publication of Cell St ...
Alzheimer's disease & dementia
Feb 21, 2013 |
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Ranibizumab may prevent retinal detachment side effect
Proliferative vitreoretinopathy (PVR), or the formation of scar tissue in the eye, is a serious, sight-threatening complication in people recovering from surgical repair of retinal detachment. PVR is difficult to predict, ...
Ophthalmology
Apr 09, 2013 |
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Pathogenesis
The pathogenesis of a disease is the mechanism by which the disease is caused. The term can also be used to describe the origin and development of the disease and whether it is acute, chronic or recurrent. The word comes from the Greek pathos, "disease", and genesis, "creation".
Types of pathogenesis include microbial infection, inflammation, malignancy and tissue breakdown.
Most diseases are caused by multiple pathogenetical processes together. For example, certain cancers arise from dysfunction of the immune system (skin tumors and lymphoma after a renal transplant, which requires immunosuppression).
Often, a potential etiology is identified by epidemiological observations before a pathological link can be drawn between the cause and the disease.
For more information about Pathogenesis, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
