HIV cure research to date has focused on clearing the virus from T cells, a type of white blood cell that is an essential part of the immune system. Yet investigators in the Division of Infectious Diseases at the University ...
Apr 17, 2017
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How retroviruses like HIV spread in their hosts had been unknown—until a Yale team devised a way to watch it actually happen in a living organism. The elaborate and sometimes surprising steps the virus takes to reach and ...
Oct 2, 2015
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Hong Kong Baptist University (HKBU) chemists have invented a new class of multifunctional cyanine compounds that can be used for detection, imaging and treatment of Alzheimer's disease. The research team was jointly led by ...
Jan 5, 2018
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High blood pressure could be caused by a common virus, according to a study carried out by a team of Chinese doctors which could lead to better treatment for millions of people around the world.
Aug 15, 2011
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A study investigating the role of Treponema denticola (T. denticola) in Alzheimer's disease (AD) pathogenesis will be presented by Zhiqun Tang of the West China Hospital of Stomatology at Sichuan University, China at the ...
Jun 25, 2022
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Enhanced cholesterol metabolism in certain immune cells may help some people infected with HIV naturally control disease progression, according to new research from the University of Pittsburgh Graduate School of Public Health.
Jul 17, 2015
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Stability in the composition of the hundred trillion bacterial cells in the human gastrointestinal tract is crucial to health, but scientists have been perplexed how our microbiota withstands an onslaught of toxins, dietary ...
Jan 9, 2015
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Researchers from Boston University School of Medicine, working with scientists across the nation on the Alzheimer's Disease Sequencing Project (ADSP), have discovered new genes that will further current understanding of the ...
Aug 14, 2018
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For decades the amyloid hypothesis has dominated the research field in Alzheimer's disease. The theory describes how an increase in secreted beta-amyloid peptides leads to the formation of plaques, toxic clusters of damaged ...
Oct 28, 2011
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(Medical Xpress) -- Yale University researchers have identified four unique host defense proteins among thousands that seem to play a crucial role in mobilizing the immune system's response to bacterial infections, they report ...
May 6, 2011
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The pathogenesis of a disease is the mechanism by which the disease is caused. The term can also be used to describe the origin and development of the disease and whether it is acute, chronic or recurrent. The word comes from the Greek pathos, "disease", and genesis, "creation".
Types of pathogenesis include microbial infection, inflammation, malignancy and tissue breakdown.
Most diseases are caused by multiple pathogenetical processes together. For example, certain cancers arise from dysfunction of the immune system (skin tumors and lymphoma after a renal transplant, which requires immunosuppression).
Often, a potential etiology is identified by epidemiological observations before a pathological link can be drawn between the cause and the disease.
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