Neuroscience

A new mutation behind synucleinopathies

Parkinson's disease and Lewy body dementia belong to a family of neurodegenerative disorders called synucleinopathies because they are caused by the pathological accumulation of protein alpha-synuclein into structures called ...

Alzheimer's disease & dementia

Three-dimensional X-ray image spotlights neurodegenerative disease

What changes occur in parts of the brain affected by neurodegenerative disease? How does the structure of the neurons change? Some pathological changes in the tissue are easy to identify using standard microscopy. For example, ...

Alzheimer's disease & dementia

Good news, bad news from Alzheimer's vaccine trial

An experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to save brain function.

Genetics

Genetic differences important in Alzheimer's diagnosis

The two used methods for detecting amyloid pathology in Alzheimer's disease do not give unambiguous results, with the risk of incorrect or delayed care interventions. Now, researchers at Karolinska Institutet in Sweden have ...

Genetics

New gene correction therapy for Duchenne muscular dystrophy

Duchenne type muscular dystrophy (DMD) is the most common hereditary muscular disease among children, leaving them wheelchair-bound before the age of 12 and reducing life expectancy. Researchers at Technical University of ...

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