News tagged with pathway

Related topics: cells · cancer

New drug target for Rett syndrome

Harvard Stem Cell Institute (HSCI) researchers have identified a faulty signaling pathway that, when corrected, in mice ameliorates the symptoms of Rett syndrome, a devastating neurological condition. The findings could lead ...

Feb 02, 2016
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When food alters gene function

As the study shows, a high-fat diet during pregnancy and lactation leads to epigenetic changes in the offspring. These changes affect metabolic pathways regulated by the gut hormone GIP, whereby the adult offspring are more ...

Feb 01, 2016
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Study gets to the heart of heart failure

A failing heart is said to be like an "engine out of fuel." To better understand the problem of energy production in heart-failure patients, researchers at Yale University and Duke University studied the underlying metabolic ...

Jan 29, 2016
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How crystals precipitate cell death

Crystal formation plays a defining role in the pathogenesis of a range of common diseases, such as gout and atherosclerosis. Ludwig-Maximilians-Universitaet (LMU) in Munich researchers led by Hans-Joachim Anders have now ...

Jan 28, 2016
popularity6 comments 0

Hacking the programs of cancer stem cells

All of the cells in a tumor are the offspring of a single, aberrant cell, but they are not all alike. Only a few retain the capacity of the original cell to create an entire tumor. Such cancer stem cells can migrate to other ...

Jan 25, 2016
popularity71 comments 0

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