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News tagged with pathway

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Key mechanism for a common form of Alzheimer's disease discovered

Scientists from the Icahn School of Medicine at Mount Sinai, in collaboration with researchers from Icelandic Heart Association, Sage Bionetworks, and other institutions, have discovered that a network of genes involved in ...

Alzheimer's disease & dementia created Apr 25, 2013 | popularity 4.6 / 5 (5) | comments 0 | with audio podcast

Scientists develop drug that slows Alzheimer's in mice

A drug developed by scientists at the Salk Institute for Biological Studies, known as J147, reverses memory deficits and slows Alzheimer's disease in aged mice following short-term treatment. The findings, ...

Alzheimer's disease & dementia created May 13, 2013 | popularity 4.2 / 5 (5) | comments 0 | with audio podcast

Hundreds of alterations and potential drug targets to starve cancer tumors identified

A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer. The analysis, conducted by researchers at Columbia University Medical Center, ...

Cancer created Apr 21, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Researchers describe how breast cancer cells acquire drug resistance

A seven-year quest to understand how breast cancer cells resist treatment with the targeted therapy lapatinib has revealed a previously unknown molecular network that regulates cell death. The discovery provides new avenues ...

Cancer created May 07, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Study uncovers mechanism for how grapes reduce heart failure associated with hypertension

A study appearing in the Journal of Nutritional Biochemistry demonstrates that grapes are able to reduce heart failure associated with chronic high blood pressure (hypertension) by increasing the activity of several genes ...

Cardiology created May 02, 2013 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

PTSD research: Distinct gene activity patterns from childhood abuse

Abuse during childhood is different. A study of adult civilians with PTSD (post-traumatic stress disorder) has shown that individuals with a history of childhood abuse have distinct, profound changes in gene activity patterns, ...

Psychology & Psychiatry created May 01, 2013 | popularity 4 / 5 (4) | comments 0 | with audio podcast

Blocking 'scaffold' protein inhibits cancer growth, study finds

(Medical Xpress)—Researchers at the Stanford University School of Medicine have devised an entirely novel way to block biological signaling pathways that, when overactive, lead to many types of cancers. They've done so ...

Cancer created Apr 22, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Growing new arteries, bypassing blocked ones

Scientific collaborators from Yale School of Medicine and University College London (UCL) have uncovered the molecular pathway by which new arteries may form after heart attacks, strokes and other acute illnesses bypassing ...

Medical research created Apr 29, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Fusion and cell death in the development of skeletal muscle

(Medical Xpress)—Membrane fusion is a highly regulated event, both inside cells, and between them. From the moment a sperm first fuses with an egg, subsequent developmental events depend upon its proper ...

Medical research created Apr 26, 2013 | popularity 4.3 / 5 (3) | comments 0 | with audio podcast report

Workplace stress poses risk to health

Stressful situations at work can have a negative impact on the cardiovascular system and the metabolism. Stress, which is transmitted by direct and indirect signaling pathways, leads to an inflammatory response in the body, ...

Psychology & Psychiatry created Apr 23, 2013 | popularity 5 / 5 (2) | comments 0

Pain is not one-dimensional, researchers say

Pain is not one-dimensional but a combination of inflammatory reactions as well as of processes in the central nervous system and memory cells. This is the result of a current study by pain researchers at ...

Medical research created May 01, 2013 | popularity 5 / 5 (2) | comments 0

Same musicians: Brand new tune

A small ensemble of musicians can produce an infinite number of melodies, harmonies and rhythms. So too, do a handful of workhorse signaling pathways that interact to construct multiple structures that comprise ...

Medical research created May 14, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Research finds spontaneous mutations are major cause of congenital heart disease

Every year, thousands of babies are born with severely malformed hearts, disorders known collectively as congenital heart disease. Many of these defects can be repaired though surgery, but researchers don't understand what ...

Cardiology created May 12, 2013 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Computer game could improve sight of visually impaired children

(Medical Xpress)—Visually impaired children could benefit from a revolutionary new computer game being developed by a team of neuroscientists and game designers.

Diseases, Conditions, Syndromes created Apr 25, 2013 | popularity 5 / 5 (1) | comments 0

Study identifies genes, pathways altered during relaxation response practice

A new study from investigators at the Benson-Henry Institute for Mind/Body Medicine at Massachusetts General Hospital (MGH) and Beth Israel Deaconess Medical Center (BIDMC) finds that elicitation of the relaxation response ...

Psychology & Psychiatry created May 01, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast