Breast cancer researchers find new drug target companion prognostic test for hormone therapy resistance
A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive ...
Cancer
Apr 01, 2013 |
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Genetic markers ID second Alzheimer's pathway
Researchers at Washington University School of Medicine in St. Louis have identified a new set of genetic markers for Alzheimer's that point to a second pathway through which the disease develops.
Alzheimer's disease & dementia
Apr 04, 2013 |
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Molecular hub links obesity, heart disease to high blood pressure
(Medical Xpress)—Obesity, heart disease, and high blood pressure (hypertension) are all related, but understanding the molecular pathways that underlie cause and effect is complicated.
Medical research
Apr 11, 2013 |
3.3 / 5 (3) |
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Researchers identify pathway that may protect against cocaine addiction
(Medical Xpress)—A study by researchers at the National Institutes of Health gives insight into changes in the reward circuitry of the brain that may provide resistance against cocaine addiction. Scientists ...
Neuroscience
Apr 16, 2013 |
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Workplace stress poses risk to health
Stressful situations at work can have a negative impact on the cardiovascular system and the metabolism. Stress, which is transmitted by direct and indirect signaling pathways, leads to an inflammatory response in the body, ...
Psychology & Psychiatry
Apr 23, 2013 |
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Pain is not one-dimensional, researchers say
Pain is not one-dimensional but a combination of inflammatory reactions as well as of processes in the central nervous system and memory cells. This is the result of a current study by pain researchers at ...
Medical research
May 01, 2013 |
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Same musicians: Brand new tune
A small ensemble of musicians can produce an infinite number of melodies, harmonies and rhythms. So too, do a handful of workhorse signaling pathways that interact to construct multiple structures that comprise ...
Medical research
May 14, 2013 |
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Common nutritional supplement offers promise in treatment of unique form of autism with epilepsy
An international team of researchers, led by scientists at the University of California, San Diego and Yale University schools of medicine, have identified a form of autism with epilepsy that may potentially be treatable ...
Autism spectrum disorders
Sep 06, 2012 |
3 / 5 (3) |
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Rare genetic disorder points to molecules that may play role in schizophrenia
Scientists studying a rare genetic disorder have identified a molecular pathway that may play a role in schizophrenia, according to new research in the October 10 issue of The Journal of Neuroscience. The findings may on ...
Genetics
Oct 09, 2012 |
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Scientists develop new method for 'extremely' early cancer detection
It may soon be possible to test a person for cancer with just a drop of their blood and a small machine. As part of a European research project, scientists have developed a device for detecting the HSP70 protein, which is ...
Cancer
Nov 02, 2012 |
4.5 / 5 (2) |
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Glutamate neurotransmission system may be involved with depression risk
Researchers using a new approach to identifying genes associated with depression have found that variants in a group of genes involved in transmission of signals by the neurotransmitter glutamate appear to increase the risk ...
Psychology & Psychiatry
Nov 13, 2012 |
4.5 / 5 (2) |
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Discovery of molecular pathway of Alzheimer's disease reveals new drug targets
The discovery of the molecular pathway that drives the changes seen in the brains of Alzheimer's patients is reported today, revealing new targets for drug discovery that could be exploited to combat the disease. The study ...
Alzheimer's disease & dementia
Nov 20, 2012 |
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International study points to inflammation as a cause of plaque buildup in heart vessels
Fifteen new genetic regions associated with coronary artery disease have been identified by a large, international consortium of scientists—including researchers at the Stanford University School of Medicine—taking a ...
Genetics
Dec 02, 2012 |
4.5 / 5 (2) |
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Immune cell suicide alarm helps destroy escaping bacteria
Cells in the immune system called macrophages normally engulf and kill intruding bacteria, holding them inside a membrane-bound bag called a vacuole, where they kill and digest them.
Immunology
Jan 24, 2013 |
4.5 / 5 (2) |
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Experimental drug combination selectively destroys lymphoma cells
Laboratory experiments conducted by scientists at Virginia Commonwealth University Massey Cancer Center suggest that a novel combination of the drugs ibrutinib and bortezomib could potentially be an effective ...
Cancer
Feb 06, 2013 |
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