Preclinical tests shows agent stops 'slippery' proteins from binding, causing Ewing sarcoma
Continuous infusion of a novel agent not only halted the progression of Ewing sarcoma in rats, while some tumors also regressed to the point that cancer cells could not be detected microscopically, say researchers at Georgetown ...
Cancer
May 15, 2013 |
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Whole genome sequencing finds new mutations to blame for a majority of brain tumor subtype
Washington University Pediatric Cancer Genome Project has identified mutations responsible for more than half of a subtype of childhood brain tumor that takes a high toll on patients. Researchers also found evidence the tumors ...
Genetics
Apr 14, 2013 |
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Two-drug combo more effective in treating sarcomas, study shows
Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have found that when given together, a two-drug combination acts synergistically in test animals modeled with sarcoma tumors. They report ...
Cancer
Apr 09, 2013 |
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Researchers to develop next generation immunotherapy for children with deadly solid tumors
Recently, research using adoptive T-cell immunotherapy in blood cancers have shown success, most notably in the case of a seven-year-old girl whose leukemia went into remission using altered T-cells and a disabled HIV virus. ...
Cancer
Apr 03, 2013 |
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Melanoma rates rising in US children
(HealthDay)—Melanoma, the most deadly form of skin cancer, doesn't usually occur in kids, but a new study shows that it's happening more often.
Cancer
Apr 03, 2013 |
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Child's cancer often causes parents severe distress: study
(HealthDay)—Many parents of children with advanced cancer have high to severe levels of psychological distress, a new study finds.
Pediatrics
Apr 02, 2013 |
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T-cell therapy eradicates an aggressive leukemia in two children
Two children with an aggressive form of childhood leukemia had a complete remission of their disease-showing no evidence of cancer cells in their bodies-after treatment with a novel cell therapy that reprogrammed their immune ...
Cancer
Mar 25, 2013 |
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Therapies for ALL and AML targeting MER receptor hold promise of more effect with less side-effect
Two University of Colorado Cancer Center studies show that the protein receptor Mer is overexpressed in many leukemias, and that inhibition of this Mer receptor results in the death of leukemia cells – without affecting ...
Cancer
Mar 11, 2013 |
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Study identifies growth factor essential to the most common malignant pediatric brain tumor
A multi-institutional team led by Massachusetts General Hospital (MGH) researchers has identified a molecular pathway that appears to be essential for the growth and spread of medulloblastoma, the most common ...
Cancer
Feb 28, 2013 |
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Tube versus IV feeding in malnourished pediatric cancer patients
About 60 percent of pediatric cancer patients experience malnourishment during treatment. At that point, patients and families have a choice: tube feeding or IV nutrition supplement. Which would you choose? A study published ...
Cancer
Feb 13, 2013 |
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Long-term side-effects of targeted therapies in pediatric cancer patients
A University of Colorado Cancer Center review published this week in the journal Lancet Oncology describes possible long-term side-effects of new, targeted therapies in pediatric cancer patients: what we don't know may hu ...
Cancer
Feb 07, 2013 |
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Study finds mutations linked to relapse of childhood leukemia
After an intensive three-year hunt through the genome, medical researchers have pinpointed mutations that leads to drug resistance and relapse in the most common type of childhood cancer—the first time anyone has linked ...
Genetics
Feb 03, 2013 |
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Gleevec's latest approval is for pediatric cancer
(HealthDay)—The anti-cancer drug Gleevec (imatinib) has received new U.S. Food and Drug Administration approval to treat the most common type of pediatric cancer, affecting some 2,900 children each year, the agency said ...
Cancer
Jan 25, 2013 |
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Gene sequencing project mines data once considered 'junk' for clues about cancer
Genome sequencing data once regarded as junk is now being used to gain important clues to help understand disease. The latest example comes from the St. Jude Children's Research Hospital – Washington University Pediatric ...
Cancer
Jan 24, 2013 |
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A genetic defect in sex cells may predispose to childhood leukemia
Researchers at the Sainte-Justine University Hospital Center and the University of Montreal have found a possible heredity mechanism that predisposes children to acute lymphoblastic leukemia (ALL), the most ...
Genetics
Dec 17, 2012 |
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