Whole genome sequencing finds new mutations to blame for a majority of brain tumor subtype
Washington University Pediatric Cancer Genome Project has identified mutations responsible for more than half of a subtype of childhood brain tumor that takes a high toll on patients. Researchers also found evidence the tumors ...
Genetics
Apr 14, 2013 |
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Study finds mutations linked to relapse of childhood leukemia
After an intensive three-year hunt through the genome, medical researchers have pinpointed mutations that leads to drug resistance and relapse in the most common type of childhood cancer—the first time anyone has linked ...
Genetics
Feb 03, 2013 |
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New gene variants raise risk of neuroblastoma, influence tumor progression
Researchers have discovered two gene variants that raise the risk of the pediatric cancer neuroblastoma. Using automated technology to perform genome-wide association studies on DNA from thousands of subjects, the study broadens ...
Genetics
Sep 04, 2012 |
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Cancer gene family member functions key to cell adhesion and migration
The WTX gene is mutated in approximately 30 percent of Wilms tumors, a pediatric kidney cancer. Like many genes, WTX is part of a family. In this case, WTX has two related siblings, FAM123A and FAM123C. While ...
Cancer
Aug 30, 2012 |
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Cancer sequencing project identifies potential approaches to combat aggressive leukemia
Researchers have discovered that a subtype of leukemia characterized by a poor prognosis is fueled by mutations in pathways distinctly different from a seemingly similar leukemia associated with a much better outcome. The ...
Cancer
Jan 11, 2012 |
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Two-drug combo more effective in treating sarcomas, study shows
Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have found that when given together, a two-drug combination acts synergistically in test animals modeled with sarcoma tumors. They report ...
Cancer
Apr 09, 2013 |
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T-cell therapy eradicates an aggressive leukemia in two children
Two children with an aggressive form of childhood leukemia had a complete remission of their disease-showing no evidence of cancer cells in their bodies-after treatment with a novel cell therapy that reprogrammed their immune ...
Cancer
Mar 25, 2013 |
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Study identifies growth factor essential to the most common malignant pediatric brain tumor
A multi-institutional team led by Massachusetts General Hospital (MGH) researchers has identified a molecular pathway that appears to be essential for the growth and spread of medulloblastoma, the most common ...
Cancer
Feb 28, 2013 |
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Gene sequencing project mines data once considered 'junk' for clues about cancer
Genome sequencing data once regarded as junk is now being used to gain important clues to help understand disease. The latest example comes from the St. Jude Children's Research Hospital – Washington University Pediatric ...
Cancer
Jan 24, 2013 |
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Using unique combination of diet and radiation therapy, researchers successfully destroy brain tumor cells
A team of brain cancer researchers at Barrow Neurological Institute at St. Joseph's Hospital and Medical Center has effectively treated brain tumor cells using a unique combination of diet and radiation therapy. The study, ...
Cancer
Dec 04, 2012 |
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Study offers clues to cause of kids' brain tumors
(Medical Xpress)—Insights from a genetic condition that causes brain cancer are helping scientists better understand the most common type of brain tumor in children.
Genetics
Nov 16, 2012 |
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Gene sequencing project identifies abnormal gene that launches rare childhood leukemia
Research led by the St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project has identified a fusion gene responsible for almost 30 percent of a rare subtype of childhood leukemia with ...
Cancer
Nov 12, 2012 |
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World's largest release of comprehensive human cancer genome data helps speed discoveries
To speed progress against cancer and other diseases, the St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project today announced the largest-ever release of comprehensive human cancer ...
Genetics
May 29, 2012 |
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Study shows girls believe HPV vaccine protects from other STDs
(Medical Xpress) -- A new study published in the Archives of Pediatric and Adolescent Medicine shows that almost a quarter of girls surveyed believe that the HPV vaccine will also help prevent other STDs. ...
Health
Jan 06, 2012 |
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Basic biology offers clues to better neuroblastoma treatments
By studying tumor biology at the molecular level, researchers are gaining a deeper understanding of drug resistance -- and how to avoid it by designing pediatric cancer treatments tailored to specific mutations in a child's ...
Cancer
Nov 09, 2011 |
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