ACR: Strontium ranelate cuts progression of knee OA
(HealthDay)—The osteoporosis therapeutic strontium ranelate (SrRan) reduces radiographic and radiological progression of knee osteoarthritis, according to a study presented at the annual meeting of the ...
Arthritis & Rheumatism
Nov 12, 2012 |
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Canada high court voids Pfizer's Viagra patent
Canada's top court on Thursday stripped Pfizer of its patent for Viagra, saying the pharmaceutical giant failed in the patent to identify the active compound in the drug.
Medications
Nov 08, 2012 |
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Once-yearly zoledronic acid benefits men with osteoporosis
(HealthDay)—For men with osteoporosis, a once-yearly infusion with zoledronic acid is associated with fewer vertebral fractures and improved bone health compared with placebo, according to a study published ...
Diseases, Conditions, Syndromes
Nov 02, 2012 |
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Latrepirdine not effective in Huntington's disease
(HealthDay)—Although safe and well tolerated, the experimental small molecule latrepirdine does not improve cognition after six months of treatment in patients with mild-to-moderate Huntington's disease ...
Neuroscience
Nov 01, 2012 |
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Insulin glargine's main metabolic effect as metabolite M1
(HealthDay)—For patients with type 2 diabetes, following administration of a subcutaneous injection of a therapeutic dose of insulin glargine, glargine is minimally detectable in blood, and most of the ...
Diabetes
Oct 25, 2012 |
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Experts call for increased neonatal inclusion in pediatric drug trials
Clinical drug trials are a vital part of pharmaceutical manufacturers gaining approval for use by the U.S. Food and Drug Administration. A Commentary scheduled for publication in The Journal of Pediatrics assesses the is ...
Pediatrics
Oct 25, 2012 |
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Tadalafil effective, safe in complete erectile dysfunction
(HealthDay)—In men with complete erectile dysfunction (ED), tadalafil 2.5 and 5 mg once-daily result an in intercourse success rate of 32.4 and 46.4 percent, respectively, according to research published ...
Diseases, Conditions, Syndromes
Oct 14, 2012 |
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Investigational drugs chosen for major Alzheimer's prevention trial
Leading scientists have selected the first drugs to be evaluated in a worldwide clinical study to determine whether they can prevent Alzheimer's disease.
Alzheimer's disease & dementia
Oct 10, 2012 |
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Physicians much less willing to prescribe drugs tested in pharmaceutical-industry funded trials, study finds
(Medical Xpress)—Physicians are less likely to trust the results of clinical trials when they know those trials were funded by pharmaceutical companies, regardless of the quality of the research, a recent ...
Medications
Oct 09, 2012 |
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'Treatment alliance' needed to save more children's lives from cancer
Experts are calling for an urgent change to approaches for treating and researching childhood cancers, to continue to save more children from the disease.
Cancer
Oct 08, 2012 |
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Biological markers increase clinical trial success rate of new breast cancer drugs
Using biological markers—genetic characteristics that are associated with some patients with breast cancer—can increase the success rate of clinical trials for breast cancer drugs by almost 50 per cent, says new research ...
Cancer
Oct 01, 2012 |
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Short-, long-course therapy comparable in T3 rectal cancer
(HealthDay)—There are no statistically significant differences in the rates of local recurrence (LR), distant recurrence, relapse-free survival, overall survival, or late toxicity in patients treated with ...
Cancer
Sep 27, 2012 |
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Public Citizen: State drug fraud cases on the rise
(AP)—A consumer advocacy group is reporting that pharmaceutical companies have paid more than $30 billion to state and federal governments to settle allegations of fraud over the last 20 years.
Medications
Sep 27, 2012 |
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Sequential oral, topical tacrolimus benefits dermatitis
(HealthDay)—Sequential therapy with oral tacrolimus and topical tacrolimus may be an effective treatment for severe atopic dermatitis (AD), according to a pilot study published in the October issue of the ...
Diseases, Conditions, Syndromes
Sep 20, 2012 |
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Can disclosure hurt the translation of research?
All major clinical trials now include disclosures detailing who funded the study to ensure transparency. However, is it possible that this transparency is actually hurting research? One might assume that the methodological ...
Other
Sep 19, 2012 |
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