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Researchers help test cancer drug in clinical trial leading to FDA approval

The FDA has approved a thyroid cancer drug successfully tested at Virginia G. Piper Cancer Center Clinical Trials, a partnership of Scottsdale Healthcare and the Translational Genomics Research Institute (TGen).

Cancer created Mar 27, 2013 | popularity not rated yet | comments 0

Malaria vaccine fails to work after four years

A new vaccine that has raised hopes of becoming a potent new tool in the battle against malaria seems to stop working in children after four years, according to research published Wednesday.

Medications created Mar 20, 2013 | popularity 1 / 5 (1) | comments 0

Cangrelor superior to clopidogrel in CHAMPION PHOENIX trial

The experimental anti-clotting drug cangrelor solidly outperformed commonly used clopidogrel in a large global trial of patients who underwent coronary stent procedures, according to data from the phase III CHAMPION PHOENIX ...

Cardiology created Mar 11, 2013 | popularity not rated yet | comments 1

Greater representation of elderly patients in Phase III trials are needed

The median age of patients diagnosed with advanced non–small-cell lung cancer (NSCLC) has steadily increased over the recent years and is presently 70 years. Despite this, the elderly are significantly underrepresented ...

Cancer created Feb 22, 2013 | popularity not rated yet | comments 0

Spin and bias in published studies of breast cancer trials

Spin and bias exist in a high proportion of published studies of the outcomes and adverse side-effects of phase III clinical trials of breast cancer treatments, according to new research published in the cancer journal Annals of ...

Cancer created Jan 09, 2013 | popularity not rated yet | comments 0 | with audio podcast

Germany's Merck suffers setback with cancer drug

German pharmaceutical company Merck KgaA says a late stage trial of a new lung cancer drug has failed to meet expectations.

Medications created Dec 19, 2012 | popularity not rated yet | comments 0

Cancer drug improves survival in patients with metastatic melanoma

(Medical Xpress)—Results of a University of Arizona Cancer Center's scientist-led clinical trial show that a drug already approved for breast and lung cancer improved progression-free survival in patients ...

Cancer created Nov 14, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Drug shrinks brain tumors in children with tuberous sclerosis complex

A drug originally developed to prevent the rejection of transplanted organs has now been shown to dramatically reduce a particular kind of brain tumor in patients with tuberous sclerosis complex (TSC)—a genetic disease ...

Cancer created Nov 13, 2012 | popularity not rated yet | comments 0 | with audio podcast

New antibody conjugate drug improves survival in older patients with acute myeloid leukaemia

(Medical Xpress)—Acute Myeloid Leukaemia (AML) patients given a new type of 'smart drug' in addition to chemotherapy treatment are 22 per cent less likely to relapse and around 13 per cent less likely to ...

Cancer created Nov 12, 2012 | popularity not rated yet | comments 0

New MS drug proves effective where others have failed

A drug which 'reboots' a person's immune system has been shown to be an effective treatment for multiple sclerosis (MS) patients who have already failed to respond to the first drug with which they were treated (a 'first-line' ...

Neuroscience created Oct 31, 2012 | popularity 5 / 5 (1) | comments 0

Cannabis extract eases muscle stiffness typical of multiple sclerosis

Cannabis seems to ease the painful muscle stiffness typical of multiple sclerosis, indicate phase III trial results, published in the Journal of Neurology Neurosurgery and Psychiatry.

Neuroscience created Oct 09, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Phase III data in treatment of renal cell carcinoma reported

New results from phase III trials exploring treatment options for patients with advanced renal cell carcinoma were released at the ESMO 2012 Congress of the European Society for Medical Oncology in Vienna.

Cancer created Oct 01, 2012 | popularity not rated yet | comments 0

Phase III trial shows crizotinib superior to single-agent chemotherapy for ALK-positive lung cancer

The results of a new phase III trial show that crizotinib, a targeted therapy, is a more effective treatment than standard chemotherapy for patients with advanced, ALK-positive lung cancer, researchers said at the ESMO 2012 ...

Cancer created Sep 30, 2012 | popularity not rated yet | comments 0

Studies show advances in gastrointestinal cancer treatments

New trial data showing improvements in the treatment of esophageal and gastrointestinal cancers were released today at the ESMO 2012 Congress of the European Society for Medical Oncology in Vienna.

Cancer created Sep 29, 2012 | popularity not rated yet | comments 0

Novel therapy helps ease pain and suffering for sickle cell patients

Chronic, debilitating pain and potential organ failure are what approximately 100,000 sickle cell patients in the United States live with each day. Yutaka Niihara, M.D., M.P.H. - lead investigator at The Los Angeles Biomedical ...

Diseases, Conditions, Syndromes created Sep 25, 2012 | popularity not rated yet | comments 0