News tagged with phenotypes
Systematic screening of med adherence will ID barriers
(HealthDay)—Implementation of systematic monitoring for medication adherence will allow for identification of barriers to adherence and tailoring of interventions, according to a viewpoint piece published ...
Health
15 hours ago |
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With two new methods, scientists hope to improve genome-wide association studies
As scientists probe and parse the genetic bases of what makes a human a human (or one human different from another), and vigorously push for greater use of whole genome sequencing, they find themselves increasingly ...
Genetics
Apr 26, 2013 |
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Protecting against aging at the molecular level
Research from Western University and Lawson Health Research Institute sheds new light on a gene called ATRX and its function in the brain and pituitary. Children born with ATRX syndrome have cognitive defects and developmental ...
Medical research
Apr 08, 2013 |
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New research on the effects of traumatic brain injury
Considerable opportunity exists to improve interventions and outcomes of traumatic brain injury (TBI) in older adults, according to three studies published in the recent online issue of NeuroRehabilitation by researchers from t ...
Neuroscience
Mar 28, 2013 |
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Maternal obesity increases the risk of frequent wheezing in offspring
The fact that excess weight during pregnancy has negative consequences is not new information. A new study now concludes that the children of mothers obese before falling pregnant are four times more likely ...
Pediatrics
Mar 08, 2013 |
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Modeling Alzheimer's disease using iPSCs
Working with a group from Nagasaki University, a research group at the Center for iPS Cell Research and Application (CiRA) at Japan's Kyoto University has announced in the Feb. 21 online publication of Cell St ...
Alzheimer's disease & dementia
Feb 21, 2013 |
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Researcher advancing motor neuron studies
A University of Connecticut researcher is advancing the understanding of the devastating inherited condition known as spinal muscular atrophy.
Neuroscience
Jan 29, 2013 |
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Female mice exposed to BPA by mothers show unexpected characteristics
Female mice exposed to Bisphenol A through their mother's diet during gestation and lactation were found to be hyperactive, exhibit spontaneous activity and had leaner body mass than those not exposed to the chemical, researchers ...
Medical research
Jan 24, 2013 |
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Mouse mutant opens new path for birth defect research
(Medical Xpress)—According to the Centers for Disease Control, nearly 3 of every 100 babies in the U.S. are born with a birth defect. Among boys, one of the most common defects is the displacement of the ...
Medical research
Jan 16, 2013 |
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Researchers discover new pathways that drive metastatic prostate cancer
Elevated levels of Cyclin D1b could function as a novel biomarker of lethal metastatic disease in prostate cancer patients, according to a pre-clinical study published ahead of print on December 21 in the Journal of Clinical In ...
Cancer
Dec 21, 2012 |
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Genotyping IDs long-term risk of macular degeneration
(HealthDay)—Genotyping of two genetic risk alleles can be used to estimate the long-term risk of early and late age-related macular degeneration (AMD), but knowing the phenotype is important in assessing ...
Ophthalmology
Nov 13, 2012 |
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Exome sequencing: Potential diagnostic assay for unexplained intellectual disability
Research findings confirming that de novo mutations represent a major cause of previously unexplained intellectual disability were presented on Nov. 8 at the American Society of Human Genetics 2012 meeting in San Francisco.
Genetics
Nov 08, 2012 |
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New autoinflammatory disease linked to NOD2 mutations ID'd
(HealthDay)—A new autoinflammatory disease characterized by features including inflammatory polyarthritis/polyarthralgia and dermatitis, and involving mutations in the nucleotide-binding oligomerization ...
Inflammatory disorders
Nov 02, 2012 |
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Studies explore racial disparities in IBD symptoms and therapy
Three separate studies presented today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas help to advance understanding of the differences between African American and Caucasian ...
Diseases, Conditions, Syndromes
Oct 22, 2012 |
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Morphology of bicuspid aortic valve influences outcomes
(HealthDay)—The morphology of bicuspid aortic valve (BAV) malformations plays an important role in outcomes, according to a study published in the Nov. 1 issue of The American Journal of Cardiology.
Cardiology
Oct 19, 2012 |
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Phenotype
A phenotype is an organism's observable characteristics or traits: such as its morphology, development, biochemical or physiological properties, behavior, and products of behavior (such as a bird's nest). Phenotypes result from the expression of an organism's genes as well as the influence of environmental factors and the interactions between the two.
The genotype of an organism is the inherited instructions it carries within its genetic code. Not all organisms with the same genotype look or act the same way because appearance and behavior are modified by environmental and developmental conditions. Similarly, not all organisms that look alike necessarily have the same genotype.
This genotype-phenotype distinction was proposed by Wilhelm Johannsen in 1911 to make clear the difference between an organism's heredity and what that heredity produces. The distinction is similar to that proposed by August Weismann, who distinguished between germ plasm (heredity) and somatic cells (the body). The Genotype-Phenotype concept should not be confused with Francis Crick's central dogma of molecular biology which is a statement about the directionality of molecular sequential information flowing from DNA to protein (but which cannot become transferred from proteins).
For more information about Phenotype, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.