News tagged with phenotypes
Systematic screening of med adherence will ID barriers
(HealthDay)—Implementation of systematic monitoring for medication adherence will allow for identification of barriers to adherence and tailoring of interventions, according to a viewpoint piece published ...
Health
May 22, 2013 |
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With two new methods, scientists hope to improve genome-wide association studies
As scientists probe and parse the genetic bases of what makes a human a human (or one human different from another), and vigorously push for greater use of whole genome sequencing, they find themselves increasingly ...
Genetics
Apr 26, 2013 |
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New class of stem cell-like cells discovered offers possibility for spinal cord repair
The Allen Institute for Brain Science announced today the discovery of a new class of cells in the spinal cord that act like neural stem cells, offering a fresh avenue in the search for therapies to treat spinal cord injury ...
Medical research
Sep 15, 2011 |
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Researcher advancing motor neuron studies
A University of Connecticut researcher is advancing the understanding of the devastating inherited condition known as spinal muscular atrophy.
Neuroscience
Jan 29, 2013 |
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Researchers weigh methods to more accurately measure genome sequencing
Lost in the euphoria of the 2003 announcement that the human genome had been sequenced was a fundamental question: how can we be sure that an individual's genome has been read correctly?
Genetics
Feb 03, 2012 |
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New autoinflammatory disease linked to NOD2 mutations ID'd
(HealthDay)—A new autoinflammatory disease characterized by features including inflammatory polyarthritis/polyarthralgia and dermatitis, and involving mutations in the nucleotide-binding oligomerization ...
Inflammatory disorders
Nov 02, 2012 |
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Female mice exposed to BPA by mothers show unexpected characteristics
Female mice exposed to Bisphenol A through their mother's diet during gestation and lactation were found to be hyperactive, exhibit spontaneous activity and had leaner body mass than those not exposed to the chemical, researchers ...
Medical research
Jan 24, 2013 |
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Protecting against aging at the molecular level
Research from Western University and Lawson Health Research Institute sheds new light on a gene called ATRX and its function in the brain and pituitary. Children born with ATRX syndrome have cognitive defects and developmental ...
Medical research
Apr 08, 2013 |
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Review: inflammation's role in obesity-colorectal cancer link
(HealthDay)—A new review summarizes the ways in which inflammation and altered metabolism are associated with colorectal cancer in obese individuals; the review was published online Sept. 3 in Obesity Re ...
Overweight and Obesity
Sep 13, 2012 |
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Studies explore racial disparities in IBD symptoms and therapy
Three separate studies presented today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas help to advance understanding of the differences between African American and Caucasian ...
Diseases, Conditions, Syndromes
Oct 22, 2012 |
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Study compares rate of death following diabetes diagnosis among normal weight and overweight adults
Participants in a study who were normal weight at the time of a diagnosis of diabetes experienced higher rates of total and noncardiovascular death compared with those who were overweight or obese at diabetes diagnosis, according ...
Diabetes
Aug 07, 2012 |
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Exome sequencing: Potential diagnostic assay for unexplained intellectual disability
Research findings confirming that de novo mutations represent a major cause of previously unexplained intellectual disability were presented on Nov. 8 at the American Society of Human Genetics 2012 meeting in San Francisco.
Genetics
Nov 08, 2012 |
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Modeling Alzheimer's disease using iPSCs
Working with a group from Nagasaki University, a research group at the Center for iPS Cell Research and Application (CiRA) at Japan's Kyoto University has announced in the Feb. 21 online publication of Cell St ...
Alzheimer's disease & dementia
Feb 21, 2013 |
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Genotyping IDs long-term risk of macular degeneration
(HealthDay)—Genotyping of two genetic risk alleles can be used to estimate the long-term risk of early and late age-related macular degeneration (AMD), but knowing the phenotype is important in assessing ...
Ophthalmology
Nov 13, 2012 |
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Maternal obesity increases the risk of frequent wheezing in offspring
The fact that excess weight during pregnancy has negative consequences is not new information. A new study now concludes that the children of mothers obese before falling pregnant are four times more likely ...
Pediatrics
Mar 08, 2013 |
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Phenotype
A phenotype is an organism's observable characteristics or traits: such as its morphology, development, biochemical or physiological properties, behavior, and products of behavior (such as a bird's nest). Phenotypes result from the expression of an organism's genes as well as the influence of environmental factors and the interactions between the two.
The genotype of an organism is the inherited instructions it carries within its genetic code. Not all organisms with the same genotype look or act the same way because appearance and behavior are modified by environmental and developmental conditions. Similarly, not all organisms that look alike necessarily have the same genotype.
This genotype-phenotype distinction was proposed by Wilhelm Johannsen in 1911 to make clear the difference between an organism's heredity and what that heredity produces. The distinction is similar to that proposed by August Weismann, who distinguished between germ plasm (heredity) and somatic cells (the body). The Genotype-Phenotype concept should not be confused with Francis Crick's central dogma of molecular biology which is a statement about the directionality of molecular sequential information flowing from DNA to protein (but which cannot become transferred from proteins).
For more information about Phenotype, read the full article at
Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.
