News tagged with phenotypes
The Allen Institute for Brain Science announced today the discovery of a new class of cells in the spinal cord that act like neural stem cells, offering a fresh avenue in the search for therapies to treat spinal cord injury ...
Medical research Sep 15, 2011 | 5 / 5 (7) | 0 |
Lost in the euphoria of the 2003 announcement that the human genome had been sequenced was a fundamental question: how can we be sure that an individual's genome has been read correctly?
Genetics Feb 03, 2012 | 5 / 5 (3) | 0
As upper level undergraduate genetics instructors plan their syllabi for the fall semester, the Genetics Society of America's GENETICS journal offers a new educational resource, articles called "Primers." These articles are de ...
Genetics Aug 09, 2012 | 5 / 5 (2) | 0
(HealthDay)—A new review summarizes the ways in which inflammation and altered metabolism are associated with colorectal cancer in obese individuals; the review was published online Sept. 3 in Obesity Re ...
Overweight and Obesity Sep 13, 2012 | 5 / 5 (1) | 0
(HealthDay)—A new autoinflammatory disease characterized by features including inflammatory polyarthritis/polyarthralgia and dermatitis, and involving mutations in the nucleotide-binding oligomerization ...
Inflammatory disorders Nov 02, 2012 | 5 / 5 (1) | 0
Research findings confirming that de novo mutations represent a major cause of previously unexplained intellectual disability were presented on Nov. 8 at the American Society of Human Genetics 2012 meeting in San Francisco.
Genetics Nov 08, 2012 | 5 / 5 (1) | 0
Elevated levels of Cyclin D1b could function as a novel biomarker of lethal metastatic disease in prostate cancer patients, according to a pre-clinical study published ahead of print on December 21 in the Journal of Clinical In ...
Cancer Dec 21, 2012 | 5 / 5 (1) | 0 |
A University of Connecticut researcher is advancing the understanding of the devastating inherited condition known as spinal muscular atrophy.
Neuroscience Jan 29, 2013 | 5 / 5 (1) | 0
Working with a group from Nagasaki University, a research group at the Center for iPS Cell Research and Application (CiRA) at Japan's Kyoto University has announced in the Feb. 21 online publication of Cell St ...
Alzheimer's disease & dementia Feb 21, 2013 | 5 / 5 (1) | 0
The fact that excess weight during pregnancy has negative consequences is not new information. A new study now concludes that the children of mothers obese before falling pregnant are four times more likely ...
Pediatrics Mar 08, 2013 | 5 / 5 (1) | 0
Research from Western University and Lawson Health Research Institute sheds new light on a gene called ATRX and its function in the brain and pituitary. Children born with ATRX syndrome have cognitive defects and developmental ...
Medical research Apr 08, 2013 | 5 / 5 (1) | 0
(HealthDay)—Genotyping of two genetic risk alleles can be used to estimate the long-term risk of early and late age-related macular degeneration (AMD), but knowing the phenotype is important in assessing ...
Ophthalmology Nov 13, 2012 | 4 / 5 (1) | 0
A phenotype is an organism's observable characteristics or traits: such as its morphology, development, biochemical or physiological properties, behavior, and products of behavior (such as a bird's nest). Phenotypes result from the expression of an organism's genes as well as the influence of environmental factors and the interactions between the two.
The genotype of an organism is the inherited instructions it carries within its genetic code. Not all organisms with the same genotype look or act the same way because appearance and behavior are modified by environmental and developmental conditions. Similarly, not all organisms that look alike necessarily have the same genotype.
This genotype-phenotype distinction was proposed by Wilhelm Johannsen in 1911 to make clear the difference between an organism's heredity and what that heredity produces. The distinction is similar to that proposed by August Weismann, who distinguished between germ plasm (heredity) and somatic cells (the body). The Genotype-Phenotype concept should not be confused with Francis Crick's central dogma of molecular biology which is a statement about the directionality of molecular sequential information flowing from DNA to protein (but which cannot become transferred from proteins).
For more information about Phenotype, read the full article at
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