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News tagged with phenotypes

New class of stem cell-like cells discovered offers possibility for spinal cord repair

The Allen Institute for Brain Science announced today the discovery of a new class of cells in the spinal cord that act like neural stem cells, offering a fresh avenue in the search for therapies to treat spinal cord injury ...

Medical research created Sep 15, 2011 | popularity 5 / 5 (7) | comments 0 | with audio podcast

Researchers weigh methods to more accurately measure genome sequencing

Lost in the euphoria of the 2003 announcement that the human genome had been sequenced was a fundamental question: how can we be sure that an individual's genome has been read correctly?

Genetics created Feb 03, 2012 | popularity 5 / 5 (3) | comments 0

New Genetics educational resource promotes active learning

As upper level undergraduate genetics instructors plan their syllabi for the fall semester, the Genetics Society of America's GENETICS journal offers a new educational resource, articles called "Primers." These articles are de ...

Genetics created Aug 09, 2012 | popularity 5 / 5 (2) | comments 0

Review: inflammation's role in obesity-colorectal cancer link

(HealthDay)—A new review summarizes the ways in which inflammation and altered metabolism are associated with colorectal cancer in obese individuals; the review was published online Sept. 3 in Obesity Re ...

Overweight and Obesity created Sep 13, 2012 | popularity 5 / 5 (1) | comments 0

New autoinflammatory disease linked to NOD2 mutations ID'd

(HealthDay)—A new autoinflammatory disease characterized by features including inflammatory polyarthritis/polyarthralgia and dermatitis, and involving mutations in the nucleotide-binding oligomerization ...

Inflammatory disorders created Nov 02, 2012 | popularity 5 / 5 (1) | comments 0

Exome sequencing: Potential diagnostic assay for unexplained intellectual disability

Research findings confirming that de novo mutations represent a major cause of previously unexplained intellectual disability were presented on Nov. 8 at the American Society of Human Genetics 2012 meeting in San Francisco.

Genetics created Nov 08, 2012 | popularity 5 / 5 (1) | comments 0

Researchers discover new pathways that drive metastatic prostate cancer

Elevated levels of Cyclin D1b could function as a novel biomarker of lethal metastatic disease in prostate cancer patients, according to a pre-clinical study published ahead of print on December 21 in the Journal of Clinical In ...

Cancer created Dec 21, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Researcher advancing motor neuron studies

A University of Connecticut researcher is advancing the understanding of the devastating inherited condition known as spinal muscular atrophy.

Neuroscience created Jan 29, 2013 | popularity 5 / 5 (1) | comments 0

Modeling Alzheimer's disease using iPSCs

Working with a group from Nagasaki University, a research group at the Center for iPS Cell Research and Application (CiRA) at Japan's Kyoto University has announced in the Feb. 21 online publication of Cell St ...

Alzheimer's disease & dementia created Feb 21, 2013 | popularity 5 / 5 (1) | comments 0

Maternal obesity increases the risk of frequent wheezing in offspring

The fact that excess weight during pregnancy has negative consequences is not new information. A new study now concludes that the children of mothers obese before falling pregnant are four times more likely ...

Pediatrics created Mar 08, 2013 | popularity 5 / 5 (1) | comments 0

Protecting against aging at the molecular level

Research from Western University and Lawson Health Research Institute sheds new light on a gene called ATRX and its function in the brain and pituitary. Children born with ATRX syndrome have cognitive defects and developmental ...

Medical research created Apr 08, 2013 | popularity 5 / 5 (1) | comments 0

Genotyping IDs long-term risk of macular degeneration

(HealthDay)—Genotyping of two genetic risk alleles can be used to estimate the long-term risk of early and late age-related macular degeneration (AMD), but knowing the phenotype is important in assessing ...

Ophthalmology created Nov 13, 2012 | popularity 4 / 5 (1) | comments 0

Phenotype

A phenotype is an organism's observable characteristics or traits: such as its morphology, development, biochemical or physiological properties, behavior, and products of behavior (such as a bird's nest). Phenotypes result from the expression of an organism's genes as well as the influence of environmental factors and the interactions between the two.

The genotype of an organism is the inherited instructions it carries within its genetic code. Not all organisms with the same genotype look or act the same way because appearance and behavior are modified by environmental and developmental conditions. Similarly, not all organisms that look alike necessarily have the same genotype.

This genotype-phenotype distinction was proposed by Wilhelm Johannsen in 1911 to make clear the difference between an organism's heredity and what that heredity produces. The distinction is similar to that proposed by August Weismann, who distinguished between germ plasm (heredity) and somatic cells (the body). The Genotype-Phenotype concept should not be confused with Francis Crick's central dogma of molecular biology which is a statement about the directionality of molecular sequential information flowing from DNA to protein (but which cannot become transferred from proteins).

For more information about Phenotype, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: genes