News tagged with philadelphia chromosome

Jak of all trades? Not of leukaemia therapy

About one in five or six cases of adult leukaemia in Western populations relates to so-called chronic myeloid leukaemia, or CML. Treatment of CML usually relies on inhibitors of the abnormal protein that causes the condition ...

Jan 30, 2012
popularity not rated yet | comments 0

Study yields new strategy against high-risk leukemia

August 29, 2013) St. Jude Children's Research Hospital scientists have identified a protein that certain high-risk acute lymphoblastic leukemia (ALL) cells need to survive and have used that knowledge to fashion a more effective ...

Aug 29, 2013
popularity not rated yet | comments 0

Marqibo approved for rare leukemia

(HealthDay) -- Marqibo (vincristine sulfate liposome injection) has been approved by the U.S. Food and Drug Administration to treat adults with a rare form of blood and bone marrow cancer, Philadelphia chromosome negative ...

Aug 10, 2012
popularity not rated yet | comments 0

Clinical trial delivers good results in leukemia patients

Huntsman Cancer Institute (HCI) researchers Michael Deininger, M.D., Ph.D., and Thomas O'Hare, Ph.D., were part of a team that found a potent oral drug, ponatinib, effective in patients who have developed resistance to standard ...

Nov 30, 2012
popularity not rated yet | comments 0

Options increase for CML patients failed by existing drugs

The U.S. Food and Drug Administration (FDA) this month expanded the options for patients with chronic myeloid leukemia and one form of acute lymphoblastic leukemia that carries the Philadelphia chromosome (Ph+ALL). It approved ...

Dec 21, 2012
popularity 5 / 5 (1) | comments 0

Iclusig approved for rare leukemias

(HealthDay)—Iclusig (ponatinib) has been approved by the U.S. Food and Drug Administration to treat two rare forms of leukemia..

Dec 16, 2012
popularity not rated yet | comments 0

Gleevec's latest approval is for pediatric cancer

(HealthDay)—The anti-cancer drug Gleevec (imatinib) has received new U.S. Food and Drug Administration approval to treat the most common type of pediatric cancer, affecting some 2,900 children each year, the agency said ...

Jan 25, 2013
popularity not rated yet | comments 0

Anchoring ABL for a better fate

Chronic Myelogenous Leukemia (CML) is a cancer of the white blood cells that is most commonly found in adults and in the elderly. Its incidence has been estimated to be 1 to 2 in 100,000 people. CML was the first cancer to ...

Aug 27, 2013
popularity not rated yet | comments 0