Survival has improved greatly in children with acute lymphocytic leukemia (ALL). But a certain form of ALL that occurs mostly in babies is still very lethal, with a survival rate below 50 percent: B-cell acute lymphoblastic ...
Jun 1, 2022
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35
Northwestern Medicine investigators have discovered a potential therapeutic target for the most common type of pancreatic cancer, according to a study published in Developmental Cell.
May 20, 2022
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85
Mitochondria serve as the main source of energy production in our cells, and endurance exercise is generally known to improve the function of mitochondria. However, the benefits of exercise in patients with primary mitochondrial ...
May 4, 2022
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65
A study published in The Journal of Pathology reveals that many cancers that carry a poor prognosis express an altered form of human telomerase reverse transcriptase (hTERT), an enzyme that regulates the expression of multiple ...
Mar 21, 2022
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4
Existing and emerging cancer drugs could be repurposed as therapies to be tested in clinical trials for people at genetic risk of Alzheimer's disease, according to a new study published in Science Advances. Research combining ...
Nov 10, 2021
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Malfunctioning of the so-called Hippo signaling pathway within animal cells leads to irregular activity of proteins that regulate genes involved in cell proliferation. Researchers have identified a key step in the process ...
Nov 2, 2021
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80
A form of cell communication called hedgehog signaling is vital for embryonic development in mammals. But aberrantly activated hedgehog signaling in multiple cancer types—including breast cancer—promotes tumor invasion, ...
Aug 16, 2021
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390
Suffering from the number one cause of death, patients with heart disease are in desperate need of new therapies. However, these new therapies rely on research using heart cells, which are not easy to access. In response, ...
Jun 22, 2021
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4
Researchers at the University of Eastern Finland have found a potential neuroprotective effect of a protein modification that could be a therapeutic target in early Alzheimer's disease. The new study investigated the role ...
May 19, 2021
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4
A team led by scientists at the UNC School of Medicine discovered an important vulnerability of the AIDS-causing retrovirus HIV, and has shown in preclinical experiments that a widely used diabetes drug, metformin, seems ...
Mar 29, 2021
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