Oncology & Cancer

Breast cancer resistance to CDK4/6 inhibitors arises in many ways

Breast cancer cells became resistant to therapeutics targeting CDK4/6, such as palbociclib (Ibrance), in multiple ways, and preclinical studies suggested different combinations of therapeutics may prevent and overcome the ...

Oncology & Cancer

More than just a backup system: PI3K-Delta in tumour surveillance

If something is really important, it's best not to rely on it. This basic principle is followed equally by human engineers – for example, the NASA space shuttle has three main engines – and by nature. Thus it could ...

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