Diseases, Conditions, Syndromes

Hunting the 'perfect protein' for malaria mRNA vaccine

After the success of mRNA vaccines against COVID-19, scientists are cautiously optimistic that the same technology can be used to tackle other widespread diseases such as malaria. The technology is promising, say vaccine ...

Diseases, Conditions, Syndromes

Hidden malaria life cycle discovered in the spleen

Groundbreaking studies published today in the New England Journal of Medicine and PLOS Medicine have found large numbers of malaria parasites hiding in the human spleen where they actively multiply in a previously unrecognized ...

Diseases, Conditions, Syndromes

First clinical evidence of drug-resistant malaria mutations gaining

New data provide the first clinical evidence that drug-resistant mutations in the malaria parasite Plasmodium falciparum may be gaining a foothold in Africa. The study, conducted in Rwanda, is published in The Lancet Infectious ...

Diseases, Conditions, Syndromes

'Mop up' malaria vaccine advances to trials in people

University of Florida researcher Rhoel Dinglasan, Ph.D., was awarded $6 million today by the Global Health Innovative Technology Fund to test a new malaria vaccine in people. The process leading to a phase 1 clinical trial ...

Medical research

When malaria parasites trick liver cells to let themselves in

A new study led by Maria Manuel Mota, group leader at Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal), now shows that malaria parasites secrete the protein EXP2 to make their entry into hepatocytes. These ...

Diseases, Conditions, Syndromes

Malaria parasites hide out in humans when it's not mosquito season

Malaria parasites survive the mosquito-free dry season by waiting silently in humans for the return of the rainy season that brings back with it mosquitoes. New research, by an international team including Penn State scientists, ...

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