News tagged with plos genetics
Related topics: genes , genome , genetic variation , mutations , immune cells
Pathway controlling cell growth revealed
A Melbourne-based research team has discovered a genetic defect that can halt cell growth and force cells into a death-evading survival state.
Cancer
Feb 18, 2013 |
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The same genetic defect causes Pompe disease in both humans and dogs
Pompe disease, a severe glycogen storage disease appearing in Lapphunds is caused by a genetic defect in acid α-glucosidase gene. The same genetic mutation also causes the equivalent disease in humans. Based ...
Genetics
Feb 15, 2013 |
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Researchers create new air sacs in mouse model of emphysema using novel growth factor
In a study of mice, researchers at Johns Hopkins have identified a new molecular pathway involved in the growth of tiny air sacs called alveoli that are crucial for breathing. The scientists say their experiments may lead ...
Medical research
Feb 14, 2013 |
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Accelerated biological aging, seen in women with Alzheimer's risk factor, blocked by hormone therapy
Healthy menopausal women carrying a well-known genetic risk factor for Alzheimer's disease showed measurable signs of accelerated biological aging, a new study has found.
Alzheimer's disease & dementia
Feb 13, 2013 |
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Villain stomach bug may have a sweet side: Researchers reveal how 'bad' gut bacteria may help control diabetes
A stomach bacterium believed to cause health problems such as gastritis, ulcers, and gastric cancer may play a dual role by balancing the stomach's ecosystem and controlling body weight and glucose tolerance, according to ...
Medical research
Feb 08, 2013 |
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Triple-negative breast cancer subtypes identified using microRNA
A new, large-scale study of triple-negative breast cancer shows that small molecules called microRNA can be used to define four subtypes of this aggressive malignancy.
Cancer
Feb 07, 2013 |
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Obesity leads to vitamin D deficiency
Obesity can lead to a lack of vitamin D circulating in the body, according to a study led by the UCL Institute of Child Health (ICH). Efforts to tackle obesity should thus also help to reduce levels of vitamin D deficiency ...
Overweight and Obesity
Feb 05, 2013 |
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Gene variants found to affect human lifespan
By broadly comparing the DNA of children to that of elderly people, gene researchers have identified gene variants that influence lifespan, either by raising disease risk or by providing protection from disease.
Genetics
Feb 04, 2013 |
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HIV-like viruses in non-human primates have existed much longer than previously thought
Viruses similar to those that cause AIDS in humans were present in non-human primates in Africa at least 5 million years ago and perhaps up to 12 million years ago, according to study published January 24 in the Open Access ...
HIV & AIDS
Jan 24, 2013 |
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Caloric restriction has a protective effect on chromosomes
One of the indicators of a cell's health is the state of its DNA and containers—the chromosomes—so when these fuse together or suffer anomalies, they can become the source of illnesses like cancer and/or ageing processes.
Medical research
Jan 23, 2013 |
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Diabetic fruit flies support buzz about dietary sugar dangers
Regularly consuming sucrose—the type of sugar found in many sweetened beverages—increases a person's risk of heart disease. In a study published January 10 in the journal PLOS Genetics, researchers at San ...
Genetics
Jan 17, 2013 |
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Epigenomic abnormalities predict patient survival in non-Hodgkins lymphoma
Think of the epigenome like a giant musical mixing board, turning up or down the expression of various genes. A University of Colorado Cancer Center study published today in the journal PLOS Genetics shows that in cancer ...
Genetics
Jan 10, 2013 |
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Sickle cells show potential to attack aggressive cancer tumors
By harnessing the very qualities that make sickle cell disease a lethal blood disorder, a research team led by Duke Medicine and Jenomic, a private cancer research company in Carmel, Calif., has developed ...
Cancer
Jan 09, 2013 |
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A history lesson from genes: Using DNA to tell us how populations change
When Charles Darwin first sketched how species evolved by natural selection, he drew what looked like a tree. The diagram started at a central point with a common ancestor, then the lines spread apart as ...
Genetics
Jan 09, 2013 |
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An embryo that is neither male nor female
So, is it a girl or a boy? This is the first question parents ask at the birth of an infant. Though the answer is obvious, the mechanism of sex determination is much less so. Researchers at the University of Geneva (UNIGE) ...
Genetics
Jan 03, 2013 |
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