A study of kidney organoids in a novel lab environment might have downstream implications for the treatment of polycystic kidney disease (PKD), an incurable condition that affects more than 12 million people worldwide.
Jan 5, 2023
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85
In order to treat patients with diabetes in the best possible way it is necessary to understand the disease mechanism. MODY type 3 (MODY3) is a monogenic hereditary form of diabetes that is caused by a genetic defect in the ...
Dec 22, 2022
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Huntington's disease is caused by repeated toxic changes in the protein huntingtin. An interdisciplinary team from the Department of Molecular Neurology and the Department of Stem Cell Biology at Universitätsklinikum Erlangen ...
Dec 8, 2022
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Alpha-1 antitrypsin deficiency (AATD) is an important and under-recognized genetic cause of liver disease. The most common mutation associated with liver disease results from a single change within the DNA sequence known ...
Dec 6, 2022
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141
To prevent testing on animals and create even more precise ways of testing therapeutics, the pharmaceutical industry is increasingly turning to human immune cells. However, the availability of cells like these has been limited ...
Dec 1, 2022
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Alcohol consumption during pregnancy poses significant peril to the healthy development of the unborn child. There is no known safe amount of alcohol during pregnancy.
Nov 18, 2022
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Human bones can recover from small fractures, but if the fractures are too large or the regrowth process is unbalanced, as is the case with osteoporosis, treatment is required. To develop treatments, animal experiments are ...
Nov 8, 2022
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Recent advances in immunotherapy for cancer have stimulated a plethora of studies aimed at developing T cells (white blood cells) and Natural Killer (NK) cells (immune cells with enzymes that can kill tumor cells or cells ...
Nov 3, 2022
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Researchers have developed a three-dimensional model that shows how exposure to cadmium might lead to congenital heart disease. Affecting nearly 40,000 newborns a year, congenital heart disease is the most common type of ...
Nov 2, 2022
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Essentially all human tissues and organs have the capacity to heal, to renew cells which are damaged or killed. In this context, the human brain behaves fundamentally differently. The vast majority of nerve cells are created ...
Oct 24, 2022
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