Medical research

Mapping human brain development

The human brain is probably the most complex organ in the entire living world and has long been an object of fascination for researchers. However, studying the brain, and especially the genes and molecular switches that regulate ...

Medical research

Project aims to achieve cell-based heart repair

Chronic heart failure—also known as cardiac insufficiency in medicine—is the most common reason for hospital admissions and one of the most frequent causes of death in the western world. In Germany alone, 4 million people ...

Cardiology

Study finds two protein pathways downregulated in postnatal heart

In work published today in Stem Cell Reports, researchers from the University of Minnesota Medical School discovered two signaling pathways that are downregulated in human hearts after birth. These pathways, mitogen-activated ...

Medical research

How microglia contribute to Alzheimer's disease

One of the hallmarks of Alzheimer's disease is a reduction in the firing of some neurons in the brain, which contributes to the cognitive decline that patients experience. A new study from MIT shows how a type of cells called ...

Oncology & Cancer

Making better, ready-made CAR T cells for cancer immunotherapy

In CAR T-cell immunotherapy, T cells from a patient's own blood are engineered to carry so-called chimeric antigen receptors (CAR) that enhance the T cells' ability to attack and kill tumor cells. While CAR-T therapy is a ...

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