An analysis of tissue samples from the autopsies of 44 people who died with COVID-19 shows that SAR-CoV-2 virus spread throughout the body—including into the brain—and that it lingered for almost eight months. The study ...
Dec 30, 2022
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Children with COVID-19 may present with new neurological symptoms involving the central and peripheral nervous systems, and splenial changes on imaging, according to a study published online July 1 in JAMA Neurology.
Jul 3, 2020
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How many people have been infected with COVID-19 to date? New evidence suggests that answering this question may be more challenging than previously thought.
Aug 2, 2022
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(Medical Xpress)—In the realm of DNA sequencing, the Polymerase Chain Reaction (PCR) is a well-established tool for amplifying a specific DNA sequence by reiteratively processing what's known as a reaction cocktail between ...
SARS-CoV-2, the coronavirus causing the global COVID-19 pandemic, uses a protein called polymerase to replicate its genome inside infected human cells. Terminating the polymerase reaction will stop the growth of the coronavirus, ...
Jun 30, 2020
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Mitochondrial genetic engineering is the adaptation of genetic engineering techniques to specific mitochondrial problems. Although it is not common to be born with severe mitochondrial issues, we will all eventually have ...
As of March 20, more than 8,700 people worldwide had died of COVID-19, the disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Caltech trustee David Ho (BS '74) of the Aaron Diamond AIDS Research ...
Mar 23, 2020
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A team of researchers led by Rensselaer Polytechnic Institute's Jonathan S. Dordick, Ph.D., Institute Professor of Chemical and Biological Engineering, has illuminated a new possibility for the treatment and prevention of ...
Jul 24, 2023
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The infection of human immunology viruses (HIV) occurs by integrating its genome into infected cells to enter an inactive state of reversible latency that evades anti-retroviral therapy. The capacity to sequence such a provirus ...
As a deadly disease that people can catch from ticks moves across the continent, the EU is seeking new tests and a vaccine for the infection.
Apr 14, 2023
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A polymerase (EC 2.7.7.6/7/19/48/49) is an enzyme whose central function is associated with polymers of nucleic acids such as RNA and DNA. The primary function of a polymerase is the polymerization of new DNA or RNA against an existing DNA or RNA template in the processes of replication and transcription. In association with a cluster of other enzymes and proteins, they take nucleotides from solvent, and catalyse the synthesis of a polynucleotide sequence against a nucleotide template strand using base-pairing interactions.
It is an accident of history that the enzymes responsible for the catalytic production of other biopolymers are not also referred to as polymerases.
One particular polymerase, from the thermophilic bacterium, Thermus aquaticus (Taq) (PDB 1BGX, EC 2.7.7.7) is of vital commercial importance due to its use in the polymerase chain reaction, a widely used technique of molecular biology.
Other well-known polymerases include:
This text uses material from Wikipedia, licensed under CC BY-SA
