News tagged with poor prognosis

Related topics: breast cancer , cancer cells , protein




New drug dramatically improves survival in Hodgkin lymphoma patients

A new cancer drug with remarkably few side effects is dramatically improving survival in Hodgkin lymphoma patients who fail other treatments and are nearly out of options.

Cancer created Jun 27, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

A new indicator for breast cancer relapse identified

Researchers at the IMIM (Institut de Recerca Hospital del Mar) have proven that the absence of the 14-3-3 protein sigma in breast cancer cells is directly associated with these cells' capacity to activate the signalling of ...

Cancer created Jun 19, 2012 | popularity not rated yet | comments 0

Mutations in JAK3 gene identified in subtype of lymphoma provide potential drug target

A substantial proportion of NK/T-cell lymphomas harbor Janus Kinase 3 gene mutations. Patients with these lymphomas might benefit from treatment with a Janus Kinase inhibitor according to a study published in Cancer Discovery, a jour ...

Cancer created Jun 15, 2012 | popularity 5 / 5 (1) | comments 0

Genetic markers hope for new brain tumor treatments

Researchers at The University of Nottingham have identified three sets of genetic markers that could potentially pave the way for new diagnostic tools for a deadly type of brain tumour that mainly targets children.

Cancer created Jun 15, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Haematopoietic stem cell transplantation increases survival in systemic sclerosis patients

Initial results from an international, investigator-initiated, open label phase III trial were presented at EULAR 2012, the Annual Congress of the European League Against Rheumatism. Data indicate that haematopoietic stem ...

Arthritis & Rheumatism created Jun 07, 2012 | popularity not rated yet | comments 0

Skp2 activates cancer-promoting, glucose-processing Akt

HER2 and its epidermal growth factor receptor cousins mobilize a specialized protein to activate a major player in cancer development and sugar metabolism, scientists report in the May 25 issue of Cell.

Cancer created May 25, 2012 | popularity not rated yet | comments 0 | with audio podcast

New protein signature of breast cancer progression identified

A protein signature that predicts overall survival in breast cancer patients has been uncovered in the most comprehensive survey of protein expression patterns in breast cancer progression to date.

Cancer created May 22, 2012 | popularity not rated yet | comments 0

Researchers use genomics to identify a molecular-based treatment for a viral skin cancer

Four years after they discovered the viral roots of a rare skin cancer, researchers at the University of Pittsburgh Cancer Institute (UPCI) and the School of Medicine have now identified a molecule activated by this virus ...

Cancer created May 09, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Gene-modified stem cell transplant protects patients from toxic side effects of chemotherapy

For the first time, scientists at Fred Hutchinson Cancer Research Center have transplanted brain cancer patients' own gene-modified blood stem cells in order to protect their bone marrow against the toxic side effects of ...

Cancer created May 09, 2012 | popularity not rated yet | comments 0 | with audio podcast

RANK protein promotes the initiation, progression and metastasis of human breast cancer

Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) have shown that overactivation of the RANK signalling pathway promotes the initiation, progression and metastasis of tumours in human breast epithelial ...

Cancer created Apr 24, 2012 | popularity not rated yet | comments 0

Researchers identify genes that may help in ovarian cancer diagnosis and prognosis

Scientists from Duke University Medical Center have determined that genes acting as molecular "on/off" switches can define clinically relevant molecular subtypes of ovarian cancer, providing ideal potential targets for use ...

Cancer created Apr 09, 2012 | popularity not rated yet | comments 0

New signaling pathway linked to breast cancer metastasis

Lymph nodes help to fight off infections by producing immune cells and filtering foreign materials from the body, such as bacteria or cancer cells. Thus, one of the first places that cancer cells are found when they leave ...

Cancer created Apr 02, 2012 | popularity not rated yet | comments 0

PI3K/mTOR pathway proteins tied to poor prognosis in breast cancer

Four proteins involved in translation, the final step of general protein production, are associated with poor prognosis in hormone-receptor-positive breast cancer when they are dysregulated, researchers reported at the AACR ...

Cancer created Apr 01, 2012 | popularity not rated yet | comments 0

Chemo-Linked factors may impact weight in breast cancer

(HealthDay) -- Adjuvant chemotherapy for early-stage breast cancer can induce weight gain and a variety of metabolic changes that may be associated with a poor prognosis for some patients, according to research ...

Cancer created Mar 29, 2012 | popularity 5 / 5 (1) | comments 0

Major study stops bladder cancer from metastasizing to lungs

The diagnosis of localized bladder cancer carries an 80 percent five-year survival rate, but once the cancer spreads, the survival rate at even three years is only 20 percent. A major study published today in the Journal of ...

Cancer created Mar 12, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast