Lymph nodes help to fight off infections by producing immune cells and filtering foreign materials from the body, such as bacteria or cancer cells. Thus, one of the first places that cancer cells are found when they leave ...
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Four proteins involved in translation, the final step of general protein production, are associated with poor prognosis in hormone-receptor-positive breast cancer when they are dysregulated, researchers reported at the AACR ...
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(HealthDay) -- Adjuvant chemotherapy for early-stage breast cancer can induce weight gain and a variety of metabolic changes that may be associated with a poor prognosis for some patients, according to research ...
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The diagnosis of localized bladder cancer carries an 80 percent five-year survival rate, but once the cancer spreads, the survival rate at even three years is only 20 percent. A major study published today in the Journal of ...
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(HealthDay) -- A sensitive and specific gene-based classifier can be used to identify BRAF mutant colon cancer tumors and a subpopulation of BRAF wild-type tumors with poor prognosis, according to a study pu ...
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(HealthDay) -- Extensive intratumor heterogeneity, seen in samples obtained from renal carcinomas, may lead to underestimation of the tumor genomics based on single tumor-biopsy samples, according to a study ...
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(Medical Xpress) -- Scientists from the Friedrich Miescher Institute for Biomedical Research describe how the protein phosphatase SHP2 promotes breast cancer with poor prognosis. As they report in the latest ...
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(Medical Xpress) -- Scientists at the University of Dundee studying an important tumour suppressor, which is involved in at least a quarter of all cancers, have uncovered new ways in which it works.
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Breast cancers expressing the protein HER2 have a particularly poor prognosis. Treatment with trastuzumab (Herceptin) benefits some patients with HER2-positive breast cancer, but it is not as effective as had been hoped. ...
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The American Society for Radiation Oncology (ASTRO) has developed a guideline on the radiotherapeutic and surgical management for newly diagnosed brain metastases. It has been published in Practical Radiation Oncology (PRO), ...
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Glioblastoma multiforme (GBM) is the most common of all malignant brain tumors that originate in the brain. Patients with GBM have a poor prognosis because it is a highly aggressive form of cancer that is commonly resistant ...
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Spanish researchers at CIC Biogune, the Cooperative Centre for Research into Biosciences and led by Dr. Maria Luz Martinez Chantar, have found a strong relationship between high levels of Hu antigen R (HuR) protein and the ...
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An investigational drug called regorafenib slowed the progression of tumors and lengthened the lives of patients with metastatic colorectal cancer, an international phase III clinical trial found. The findings were presented ...
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Melbourne researchers have discovered that acute myeloid leukaemia (AML), an aggressive blood cancer with poor prognosis, may be susceptible to medications that target a protein called Mcl-1.
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Researchers have discovered that a subtype of leukemia characterized by a poor prognosis is fueled by mutations in pathways distinctly different from a seemingly similar leukemia associated with a much better outcome. The ...
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