Scientists at the University of Washington (UW) in Seattle have determined the atomic architecture of a sodium channel. The achievement opens new possibilities for molecular medicine researchers around the world in designing ...
Jul 13, 2011
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Because viruses have to hijack someone else's cell to replicate, they've gotten very good at it—inventing all sorts of tricks.
Jan 25, 2024
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UNSW medical researcher Dr. David Jacques and his team have discovered how the human immunodeficiency virus (HIV) breaches the cell nucleus to establish infection, a finding that has implications beyond HIV biology.
Jan 24, 2024
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Many common diseases such as arteriosclerosis and diabetes or neurodegenerative diseases such as Alzheimer's are associated with inflammatory processes. A better understanding of these processes is therefore an important ...
Nov 2, 2023
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Several types of cancer are believed to be linked to alterations of macromolecular structures known as nuclear pore complexes (NPCs). These structures are embedded in the nuclear envelope, a membrane barrier that separates ...
Sep 15, 2023
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As heart cells mature in mice, the number of communication pathways called nuclear pores dramatically decreases, according to new research from University of Pittsburgh and UPMC scientists. While this might protect the organ ...
Oct 24, 2022
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Anita Göndör's group has identified a new mechanism underlying the pathological over-expression of cancer genes. The results, which are published in Nature Communications show that signals in the environment of the cancer ...
Jan 12, 2022
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Adenoviruses have a linchpin protein that stabilizes their DNA until it reaches the infected cell's nucleus. The protein then detaches from the viral genome, and the virus uncoats. Only then are the genes released into the ...
Dec 21, 2021
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Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and fatal degenerative disease affecting the nerve cells in the brain and spinal cord responsible for controlling voluntary muscle movement. "Sporadic" or non-inherited ...
Jul 28, 2021
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Spinal cord injuries can be life-changing and alter many important neurological functions. Unfortunately, clinicians have relatively few tools to help patients regain lost functions.
Mar 9, 2021
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