The electrical impulse that powers the workings of the brain and the heart begins with charged particles passing through cellular structures known as ion channels. Using the same technique used to decode the structure of ...
Mar 24, 2015
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Certain types of early-onset epilepsy are caused by previously unknown mutations of a potassium channel gene, KCNA2. The mutations disrupt the electrical balance in the brain in two ways. In some patients, the flow of potassium ...
Mar 11, 2015
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A new study has revealed important details of a molecular signaling system in the brain that is involved in the control of body weight and metabolism. The study, published January 19 in Nature, provides a new understanding ...
Jan 20, 2015
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An international research consortium has discovered a new gene underlying progressive myoclonus epilepsy, one of the most devastating forms of epilepsy. The study showed that a single mutation in a potassium ion channel gene ...
Nov 17, 2014
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A new discovery relating to one of the most common processes in human cells is being described as a 'paradigm shift' in understanding.
Oct 16, 2014
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Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich have chemically modified an anti-diabetic agent so as to make its action dependent on light. The resulting prototype compound, termed JB253, induces release of ...
Oct 14, 2014
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A gene crucial for brain and heart development may also be associated with sudden unexplained death in epilepsy (SUDEP), the most common cause of early mortality in epilepsy patients.
Sep 3, 2014
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A research team from the Friedman Brain Institute of the Icahn School of Medicine at Mount Sinai has published evidence that shows that subtle changes of inhibitory signaling in the reward pathway can change how animals respond ...
May 12, 2014
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(Medical Xpress)—The heart's cellular blueprint has been the subject of scientific debate for decades, with no component causing more trouble the KCNE1.
Mar 4, 2014
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Neurons transmit information with the help of special channels that allow the passage of potassium ions. Defective potassium channels play a role in epilepsy and depression. The scientists working with Prof. Henning Stahlberg ...
Jan 28, 2014
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