Medical research

Inactivation of taste genes causes male sterility

Scientists from the Monell Center report the surprising finding that two proteins involved in oral taste detection also play a crucial role in sperm development.

Medical research

New compound overcomes drug-resistant Staph infection in mice

Researchers have discovered a new compound that restores the health of mice infected with methicillin-resistant Staphylococcus aureus (MRSA), an otherwise dangerous bacterial infection. The new compound targets an enzyme ...

Oncology & Cancer

Small molecules can starve cancer cells

All cells in our body have a system that can handle cellular waste and release building blocks for recycling. The underlying mechanism is called autophagy and literally means "self-eating". Many cancer cells have increased ...

Medications

Computer program narrows drug candidates for treating COVID-19

While vaccination and public education concerning the transmission of the coronavirus causing COVID-19 have been at the forefront of our response to the pandemic, there remains an urgent need for pharmaceutical interventions ...

Diseases, Conditions, Syndromes

Penn study identifies potent inhibitor of Zika entry into human cells

A panel of small molecules that inhibit Zika virus infection, including one that stands out as a potent inhibitor of Zika viral entry into relevant human cell types, was discovered by researchers from the Perelman School ...

Diseases, Conditions, Syndromes

Scientific methods identify potential antivirals against chikungunya

Chikungunya virus has caused two recent massive outbreaks sickening millions of people. Now a team of researchers has shown that several existing compounds have potent activity against the critical CHIKV protease enzyme. ...

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