News tagged with potent inhibitors

Protein in blood exerts natural anti-cancer protection

Researchers from Thomas Jefferson University's Kimmel Cancer Center have discovered that decorin, a naturally occurring protein that circulates in the blood, acts as a potent inhibitor of tumor growth modulating the tumor ...

Jul 02, 2013
popularity not rated yet | comments 0 | with audio podcast

ASCO: Case of acquired resistance to crizotinib ID'd

(HealthDay)—A case of acquired resistance to crizotinib has been described in a patient with metastatic lung adenocarcinoma harboring a CD74-ROS1 rearrangement, according to a brief report published online ...

Jun 03, 2013
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Malaria drug treatment breakthrough

An international study, involving researchers from Griffith University's Eskitis Institute, has discovered a molecule which could form the basis of powerful new anti-malaria drugs.

Mar 22, 2013
popularity 4.3 / 5 (4) | comments 0 | with audio podcast

New mechanism of action for PARP inhibitors discovered

New understanding of how drugs called PARP inhibitors, which have already shown promise for the treatment of women with familial breast and ovarian cancers linked to BRCA mutations, exert their anticancer effects has led ...

Nov 09, 2012
popularity 4 / 5 (1) | comments 0

Small molecules can starve cancer cells

All cells in our body have a system that can handle cellular waste and release building blocks for recycling. The underlying mechanism is called autophagy and literally means "self-eating". Many cancer cells have increased ...

Oct 09, 2011
popularity 3.8 / 5 (4) | comments 0 | with audio podcast