Using genetic tools in mice, researchers at Johns Hopkins Medicine say they have identified a pair of proteins that precisely control when sound-detecting cells, known as hair cells, are born in the mammalian inner ear. The ...
Aug 5, 2019
1
10927
The amyloid precursor protein has always been vilified as a major cause of Alzheimer's disease. One of its fragments, the amyloid-beta peptide, can break off and accumulate in the brain, giving rise to the puffy white globs ...
Jun 14, 2019
0
409
Researchers at Duke-NUS Medical School, Singapore, have developed an approach to regenerate heart muscle using stem cells. Their method for priming stem cells to become heart tissues could potentially enable heart regeneration ...
Mar 22, 2019
0
871
An international team of researchers has discovered a new binding partner for amyloid precursor protein (APP)—a neurotransmitter called GABABR1a. In their paper published in the journal Science, the group describes their ...
Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now found a cause for frequent catastrophic events in the genetic material of cancer cells that have only been known for a few ...
Nov 12, 2018
0
103
Researchers led by a UCLA bioengineer have developed a therapy—based on two types of cells joined into a single unit—that could help strengthen existing treatments for acute myeloid leukemia. One of the cells is a blood ...
Oct 30, 2018
0
118
Investigators at Children's Hospital Los Angeles have been able to pinpoint the exact stage of development of the human retina, when cells can grow out of control and form cancer-like masses. The finding could open the door ...
Sep 14, 2018
0
178
A major hurdle to using neural stem cells derived from genetically different donors to replace damaged or destroyed tissues, such as in a spinal cord injury, has been the persistent rejection of the introduced material (cells), ...
May 9, 2018
0
114
New research provides the first molecular understanding of why people gain weight due to chronic stress, disrupted circadian rhythms and treatment with glucocorticoid drugs: It's all in the timing of the dips and rises of ...
Apr 3, 2018
1
348
Dramatic calorie restriction, diets reduced by 40 percent of a normal calorie total, have long been known to extend health span, the duration of disease-free aging, in animal studies, and even to extend life span in most ...
Feb 22, 2018
0
140
