Alzheimer's disease & dementia

Trial drug shows 'impressive' Alzheimer's action: study

An experimental drug cleared protein buildup in the brains of people with mild Alzheimer's disease and slowed their mental decline, the results of a preliminary trial showed Wednesday.

Alzheimer's disease & dementia

Dysfunctional endosomes are early sign of neurodegeneration

Writing in the April 11 issue of the Journal of Clinical Investigation, researchers at University of California, San Diego School of Medicine say abnormalities in a protein that helps transport and sort materials inside cells ...

Alzheimer's disease & dementia

Researchers work to block harmful behavior of key Alzheimer's enzyme

Enzymes rarely have one job. So, attempts to shut down the enzyme that causes the hallmarks of Alzheimer's disease often mean side effects, because these therapies prevent the enzyme from carrying out many other functions. ...

Genetics

Can gene therapy provide a breakthrough in Alzheimer's disease?

Therapeutic gene transfer to specific brain regions in animal models of Alzheimer's disease has uncovered multiple potential treatment approaches that deserve to be considered as candidates for clinical applications, according ...

Medical research

Duchenne muscular dystrophy is a stem cell disease

A new study from The Ottawa Hospital and the University of Ottawa is poised to completely change our understanding of Duchenne muscular dystrophy and pave the way for far more effective treatments.

Alzheimer's disease & dementia

New findings in Alzheimers research

Current Alzheimer's research focuses on the amyloid precursor protein (APP), which is responsible for the formation of destructive plaques in the brain. Researchers from Bochum have now demonstrated that APP, in addition ...

Neuroscience

Protein repairs nerve cell damage

In laboratory experiments on the basic mechanisms that cause Alzheimer's dementia, an international research team led by Heidelberg neurobiologist Prof. Dr. Ulrike Müller and a team of French scientists have succeeded in ...

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