Medical research

Timing of stress-hormone pulses controls weight gain, study finds

New research provides the first molecular understanding of why people gain weight due to chronic stress, disrupted circadian rhythms and treatment with glucocorticoid drugs: It's all in the timing of the dips and rises of ...

Medical research

Low-calorie diet enhances intestinal regeneration after injury

Dramatic calorie restriction, diets reduced by 40 percent of a normal calorie total, have long been known to extend health span, the duration of disease-free aging, in animal studies, and even to extend life span in most ...

Alzheimer's disease & dementia

Researchers successfully reverse Alzheimer's disease in mouse model

A team of researchers from the Cleveland Clinic Lerner Research Institute have found that gradually depleting an enzyme called BACE1 completely reverses the formation of amyloid plaques in the brains of mice with Alzheimer's ...

Alzheimer's disease & dementia

New player in Alzheimer's disease pathogenesis identified

Scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) have shown that a protein called membralin is critical for keeping Alzheimer's disease pathology in check. The study, published in Nature Communications, ...

Neuroscience

A star is born: Lesser-known brain cell takes center stage

Neurons have long enjoyed the spotlight in neuroscience—and for good reason: they are incredibly important cellular actors. But, increasingly, star-shaped support cells called astrocytes are being seen as more than bit ...

Diabetes

Inducing an identity crisis in liver cells may help diabetics

It is now possible to reprogram cells from the liver into the precursor cells that give rise to the pancreas by altering the activity of a single gene. A team of researchers at the Max Delbrück Center for Molecular Medicine ...

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