Some viral diseases could possibly contribute to neurodegeneration. DZNE researchers report this in the journal Nature Communications. Their assessment is based on laboratory experiments in which they were able to show that ...
Oct 19, 2021
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Case Western Reserve University researchers studying prions—misfolded proteins that cause lethal incurable diseases—have identified for the first time surface features of human prions responsible for their replication ...
Jun 17, 2021
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A "cluster" of patients experiencing hallucinations and memory loss has doctors in northeast Canada concerned that they're seeing a new kind of brain disease.
Apr 1, 2021
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For the first time, researchers have pinpointed what causes normal proteins to convert to a diseased form, causing conditions like CJD and Kuru.
Mar 15, 2021
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Approximately two years after establishing a human cerebral organoid system to study Creutzfeldt-Jakob disease (CJD), National Institutes of Health researchers have further developed the model to screen drugs for potential ...
Mar 9, 2021
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Prion diseases are a group of rapidly progressive, fatal and infectious neurodegenerative disorders affecting both humans and animals. Bovine spongiform encephalopathy (BSE) or "mad cow" disease is one of the most famous ...
Feb 22, 2021
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The earliest eye damage from prion disease takes place in the cone photoreceptor cells, specifically in the cilia and the ribbon synapses, according to a new study of prion protein accumulation in the eye by National Institutes ...
Jan 29, 2021
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One of the hallmarks of Alzheimer's disease is the formation of amyloid plaques—sticky clumps of a protein called amyloid beta—that collect between neurons in the brain. Increasingly, however, attention has turned from ...
Nov 2, 2020
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Antibodies targeting the normal PrP version of the prion protein have been found in humans selected at random with no history of any associated transmissible spongiform encephalopathies. The significance is that prion proteins ...
Aug 17, 2020
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A new study in Nucleic Acids Research, published by Oxford University Press, suggests a possible effective treatment strategy for patients suffering from prion disease.
Aug 10, 2020
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