News tagged with proceedings of the national academy of sciences

Related topics: brain , cells , genes , protein , stem cells




Scientists identify first potentially effective therapy for human prion disease

Human diseases caused by misfolded proteins known as prions are some of most rare yet terrifying on the planet—incurable with disturbing symptoms that include dementia, personality shifts, hallucinations ...

Medical research created Apr 03, 2013 | popularity 5 / 5 (5) | comments 1 | with audio podcast

Fatty acid metabolite shows promise against cancer in mice

A team of UC Davis scientists has found that a product resulting from a metabolized omega-3 fatty acid helps combat cancer by cutting off the supply of oxygen and nutrients that fuel tumor growth and spread of the disease.

Cancer created Apr 02, 2013 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Researchers see more realistic tumor growth and response to anti-cancer drugs using polymer scaffolds   

(Medical Xpress)—Porous polymer scaffolds fabricated to support the growth of biological tissue for implantation may hold the potential to greatly accelerate the development of cancer therapeutics.

Cancer created Apr 02, 2013 | popularity 3 / 5 (1) | comments 0 | with audio podcast

Newly identified tumor suppressor provides therapeutic target for prostate cancer

Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have identified how an enzyme called PKCζ suppresses prostate tumor formation. The finding, which also describes a molecular chain ...

Cancer created Apr 01, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Loss of tumor suppressor SPOP releases cancer potential of SRC-3

Mutations in a protein called SPOP (speckle-type POZ protein) disarm it, allowing another protein called steroid receptor coactivator-3 (SRC-3) to encourage the proliferation and spread of prostate cancer cells, said researchers ...

Cancer created Apr 01, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Breast cancer researchers find new drug target companion prognostic test for hormone therapy resistance

A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive ...

Cancer created Apr 01, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

New insights into how genes turn on and off

Researchers at UC Davis and the University of British Columbia have shed new light on methylation, a critical process that helps control how genes are expressed. Working with placentas, the team discovered that 37 percent ...

Genetics created Mar 27, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Transmission routes of spreading protein particles

In diseases like Alzheimer's and Parkinson's endogenous proteins accumulate in the brain, eventually leading to the death of nerve cells. These deposits, which consist of abnormally formed proteins, are supposed to migrate ...

Neuroscience created Mar 27, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Details of gene pathways suggest fine-tuning drugs for child brain tumors

Pediatric researchers, investigating the biology of brain tumors in children, are finding that crucial differences in how the same gene is mutated may call for different treatments. A new study offers glimpses into how scientists ...

Cancer created Mar 26, 2013 | popularity not rated yet | comments 0 | with audio podcast

Gene therapy may aid failing hearts

In an animal study, researchers at the University of Washington show that it was possible to use gene therapy to boost heart muscle function. The finding suggests that it might be possible to use this approach to treat patients ...

Genetics created Mar 26, 2013 | popularity 5 / 5 (1) | comments 1 | with audio podcast

Study finds brain origins of variation in pathological anxiety

New findings from nonhuman primates suggest that an overactive core circuit in the brain, and its interaction with other specialized circuits, accounts for the variability in symptoms shown by patients with severe anxiety. ...

Psychology & Psychiatry created Mar 25, 2013 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Team discovers new strategy to effectively treat, prevent osteoarthritis

Think new discoveries are the bee's knees? This one is even better—this research out of Rhode Island Hospital is the mice's knees. Researchers have found that adding lubricin, a protein that our bodies naturally produce, ...

Arthritis & Rheumatism created Mar 25, 2013 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Hunger-spiking neurons could help control autoimmune diseases

Neurons that control hunger in the central nervous system also regulate immune cell functions, implicating eating behavior as a defense against infections and autoimmune disease development, Yale School of Medicine researchers ...

Immunology created Mar 25, 2013 | popularity 4.2 / 5 (5) | comments 0 | with audio podcast

Study shows that blocking an inflammation pathway prevents cardiac fibrosis

(Medical Xpress)—New research from UC Davis published in the Proceedings of the National Academy of Sciences shows that blocking an enzyme that promotes inflammation can prevent the tissue damage following a heart attack ...

Medical research created Mar 22, 2013 | popularity 5 / 5 (5) | comments 0 | with audio podcast

Discovery could increase efficacy of promising cystic fibrosis drug

(Medical Xpress)—A little more than a year after the FDA approved Kalydeco (Vx-770), the first drug of its kind to treat the underlying cause of cystic fibrosis, University of Missouri researchers believe ...

Medical research created Mar 21, 2013 | popularity 4.5 / 5 (2) | comments 0 | with audio podcast