RANK protein promotes the initiation, progression and metastasis of human breast cancer
Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) have shown that overactivation of the RANK signalling pathway promotes the initiation, progression and metastasis of tumours in human breast epithelial ...
Cancer
Apr 24, 2012 |
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Researchers identify genes that may help in ovarian cancer diagnosis and prognosis
Scientists from Duke University Medical Center have determined that genes acting as molecular "on/off" switches can define clinically relevant molecular subtypes of ovarian cancer, providing ideal potential targets for use ...
Cancer
Apr 09, 2012 |
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New signaling pathway linked to breast cancer metastasis
Lymph nodes help to fight off infections by producing immune cells and filtering foreign materials from the body, such as bacteria or cancer cells. Thus, one of the first places that cancer cells are found when they leave ...
Cancer
Apr 02, 2012 |
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PI3K/mTOR pathway proteins tied to poor prognosis in breast cancer
Four proteins involved in translation, the final step of general protein production, are associated with poor prognosis in hormone-receptor-positive breast cancer when they are dysregulated, researchers reported at the AACR ...
Cancer
Apr 01, 2012 |
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Chemo-Linked factors may impact weight in breast cancer
(HealthDay) -- Adjuvant chemotherapy for early-stage breast cancer can induce weight gain and a variety of metabolic changes that may be associated with a poor prognosis for some patients, according to research ...
Cancer
Mar 29, 2012 |
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Genetic abnormality offers diagnostic hope for children's cancer
A chromosomal abnormality in children with a deadly form of brain cancer is linked with a poorer chance of survival, clinician scientists at The University of Nottingham have discovered.
Cancer
Mar 28, 2012 |
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Cancer cells in blood predict chances of survival and can help target breast cancer treatment
Detecting the presence of circulating tumour cells (CTCs) in the blood of women with early breast cancer after surgery but before the start of chemotherapy can provide useful information about their chances of surviving the ...
Cancer
Mar 22, 2012 |
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Major study stops bladder cancer from metastasizing to lungs
The diagnosis of localized bladder cancer carries an 80 percent five-year survival rate, but once the cancer spreads, the survival rate at even three years is only 20 percent. A major study published today in the Journal of ...
Cancer
Mar 12, 2012 |
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Gene-based test identifies poor-prognosis colon cancers
(HealthDay) -- A sensitive and specific gene-based classifier can be used to identify BRAF mutant colon cancer tumors and a subpopulation of BRAF wild-type tumors with poor prognosis, according to a study pu ...
Cancer
Mar 09, 2012 |
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Lung adenocarcinoma architecture predicts survival
(HealthDay) -- A new method of classifying invasive pulmonary adenocarcinomas, based on the predominant architecture developed by the International Association for the Study of Lung Cancer (IASLC)/American ...
Cancer
Mar 08, 2012 |
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Intratumor heterogeneity seen in renal carcinomas
(HealthDay) -- Extensive intratumor heterogeneity, seen in samples obtained from renal carcinomas, may lead to underestimation of the tumor genomics based on single tumor-biopsy samples, according to a study ...
Cancer
Mar 08, 2012 |
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Family members of ICU patients too optimistic when faced with grim prognoses
Family members of patients in the intensive care unit (ICU) tend to be overly optimistic about the possibility of recovery despite being told that the prognosis is grim, according to a study led by researchers at the University ...
Health
Mar 05, 2012 |
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Difficult discussions now can ease difficult decisions later for patients with heart failure
Patients with advanced heart failure should have ongoing conversations with their healthcare providers to make informed decisions about treatment options that match their personal values, goals and preferences, according ...
Cardiology
Mar 05, 2012 |
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Barriers identified to pediatric advance care discussions
(HealthDay) -- Prognostic understanding and parental attitude are significant barriers to advance care discussions (ACD) for children with life-threatening conditions, according to a study published online ...
Other
Mar 05, 2012 |
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Next-generation DNA sequencing to improve diagnosis for muscular dystrophy
Scientists at The University of Nottingham have used a revolutionary new DNA-reading technology for a research project that could lead to correct genetic diagnosis for muscle-wasting diseases.
Medical research
Mar 05, 2012 |
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