When oxygen is short, EGFR prevents maturation of cancer-fighting miRNAs
Even while being dragged to its destruction inside a cell, a cancer-promoting growth factor receptor fires away, sending signals that thwart the development of tumor-suppressing microRNAs (miRNAs) before it's dissolved, researchers ...
Cancer
May 23, 2013 |
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Scientists define a new mechanism leading to tumor hypoxia
An article published recently in Tumor Microenvironment and Therapy - an open access journal by Versita, defines a novel mechanism of tumor hypoxia induced by the longitudinal gradient of residual oxygen along tumor vessel ...
Cancer
May 09, 2013 |
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One-year survival up for critical congenital heart defects
(HealthDay)—For infants with critical congenital heart defects (CCHDs), one-year survival has improved over time, with an increased risk of mortality associated with earlier diagnosis, low birth weight, ...
Pediatrics
Apr 22, 2013 |
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Association between genetic mutation and risk of death for patients with thyroid cancer
Presence of the genetic mutation BRAF V600E was significantly associated with increased cancer-related death among patients with papillary thyroid cancer (PTC); however, because overall mortality in PTC is low and the association ...
Cancer
Apr 09, 2013 |
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Researchers say one specific microrna promotes tumor growth and cancer spread
Researchers at Moffitt Cancer Center have determined that the overexpression of microRNA-155 (miR-155), a short, single strand of ribonucleic acid encoded by the miR-155 host gene, promotes the growth of blood vessels in ...
Cancer
Apr 03, 2013 |
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Circulatory system mortality declining in Hodgkin's
(HealthDay)—Among patients treated for Hodgkin's lymphoma (HL), long-term excess mortality due to diseases of the circulatory system (DCS) is expected to continue to decline, according to research published ...
Cancer
Mar 09, 2013 |
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CT texture analysis of tumors may be a valuable biomarker in localized esophageal cancer
CT texture analysis of primary tumors may be a potential imaging biomarker in localized esophageal cancer following neoadjuvant chemotherapy, according to research being presented at the 2013 Cancer Imaging and Radiation ...
Cancer
Feb 08, 2013 |
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EGFR mutation not prognostic factor in non-small cell lung cancer
Recent studies have demonstrated that molecular-targeted agents, such as epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI), may prolong survival of selected patients based on tumor biomarkers. The presence ...
Cancer
Jan 15, 2013 |
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Centralization to fewer surgeons results in better survival after esophageal cancer surgery
Patients who undergo surgery for oesophageal cancer have a much greater chance of long term survival if the operation is carried out by a surgeon who has performed this particular operation many times before. This according ...
Cancer
Jan 07, 2013 |
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PR+ cells add prognostic value in luminal A breast cancer
(HealthDay)—Semiquantitative immunohistochemical expression of progesterone receptor-positive tumor cells improves prediction of survival within luminal A breast cancers, according to a study published ...
Cancer
Dec 17, 2012 |
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Prognosis after cystectomy not affected by smoking
(HealthDay)—Despite the link between cigarette smoking and the development of bladder cancer, the prognosis of people with bladder cancer after undergoing a cystectomy is not affected by cigarette smoking, ...
Cancer
Oct 15, 2012 |
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HIV status doesn't influence Hodgkin's lymphoma outcome
(HealthDay)—Despite more extensive disease and more adverse prognostic factors, HIV-positive patients with Hodgkin's lymphoma (HL) do not have worse outcomes when treated with doxorubicin, bleomycin, vinblastine, ...
Cancer
Oct 11, 2012 |
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Technique using CT linked with improved detection of lymph node metastasis in patients with melanoma
Preoperative 3-dimensional visualization of sentinel lymph nodes (SLNs) with a technique known as single-photon emission computed tomography/computed tomography was associated with a higher rate of detection of positive SLNs ...
Cancer
Sep 11, 2012 |
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Breast cancer patients with high density mammograms do not have increased risk of death
(Medical Xpress)—High mammographic breast density, which is a marker of increased risk of developing breast cancer, does not seem to increase the risk of death among breast cancer patients, according to a study led by Gretchen ...
Cancer
Sep 07, 2012 |
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Pretreatment PET/CT imaging of lymph nodes predicts recurrence in breast cancer patients
Disease-free survival for invasive ductal breast cancer (IDC) patients may be easier to predict with the help of F-18-fludeoxyglucose positron emission tomography (PET)/computed tomography (CT) scans, according to research ...
Cancer
Sep 04, 2012 |
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