Lung cancer is the predominant cause of cancer related deaths. Within the main types of lung cancers, small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC), NSCLC accounts for approximately 85%, with a poor ...
Mar 16, 2020
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A long-hidden metabolic system in cells could lead to new strategies for therapeutic cancer treatments in future.
Jan 21, 2020
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Scientists have developed new drug compounds that thwart the pro-cancer activity of FOXM1, a transcription factor that regulates the activity of dozens of genes. The new compounds suppress tumor growth in human cells and ...
Jan 7, 2020
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Researchers at the University of Toronto have identified a key protein that supports the growth of many colorectal cancers. The study, which will be published December 27 in the Journal of Cell Biology, reveals that a protein ...
Dec 27, 2019
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Palbociclib is clinically approved for use in treating breast cancer, but according to a new study, the molecular mechanism behind the drug's effectiveness is not what scientists had thought it was.
Dec 18, 2019
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Targeted, highly effective cancer treatments often produce debilitating side effects. This is the case with one commonly used therapy which works by blocking the epidermal growth factor receptor (EGFR), a protein that stimulates ...
Dec 12, 2019
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A recent study published in Oncotarget found molecular subtypes based on copy number, DNA methylation, and mRNA expression had variable proliferation levels, the highest correlating with decreased survival.
Dec 11, 2019
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With unexpected findings about a protein that's highly expressed in fat tissue, scientists at Scripps Research have opened the door to critical new understandings about obesity and metabolism. Their discovery, which appears ...
Nov 21, 2019
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Glioblastoma multiforme, or GBM, is the most frequently occurring and gravest primary tumor of the central nervous system in adults. Poor survival rates among patients with GBM are associated with the development of resistance ...
Nov 14, 2019
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Scientists from Basel have investigated the activity of stem cells in the brain of mice and discovered a key mechanism that controls cell proliferation. According to the researchers, the gene regulator Id4 controls whether ...
Aug 28, 2019
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