News tagged with proof of concept
HIV 'cure' in infancy, caution experts
AIDS experts cautioned Monday against hype of a cure after doctors in the United States suppressed HIV in a child born with the virus by administering a potent drug cocktail shortly after birth. ...
HIV & AIDS
Mar 04, 2013 |
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Scientists find way to image brain waste removal process, may lead to Alzheimer's diagnostic
(Medical Xpress)—A novel way to image the entire brain's glymphatic pathway, a dynamic process that clears waste and solutes from the brain that otherwise might build-up and contribute to the development ...
Neuroscience
Feb 25, 2013 |
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Experimental agent briefly eases depression rapidly in test: Works in brain like ketamine, with fewer side effects
(Medical Xpress)—A drug that works through the same brain mechanism as the fast-acting antidepressant ketamine briefly improved treatment-resistant patients' depression symptoms in minutes, with minimal untoward side effects, ...
Psychology & Psychiatry
Dec 11, 2012 |
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Morning vs nighttime replacement affects adverse events with extended-wear contact lenses
For people using 30-day extended-wear/continuous-wear (EW/CW) contact lenses, replacing lenses at night doesn't lower the risk of complications compared to changing lenses monthly, suggests a study – "The Effect of Daily ...
Ophthalmology
Dec 10, 2012 |
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Study advances use of stem cells in personalized medicine
Johns Hopkins researchers report concrete steps in the use of human stem cells to test how diseased cells respond to drugs. Their success highlights a pathway toward faster, cheaper drug development for some genetic illnesses, ...
Medical research
Nov 26, 2012 |
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In lab, drug-on-the-cob fights rare disease
Biologists in Canada have made a medical enzyme using genetically-engineered corn, a feat that could one day slash the cost of treating a life-threatening inherited disease, a journal reported on Tuesday.
Diseases, Conditions, Syndromes
Sep 18, 2012 |
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Antisense approach promising for treatment of parasitic infections
A targeted approach to treating toxoplasmosis, a parasitic disease, shows early promise in test-tube and animal studies, where it prevented the parasites from making selected proteins. When tested in newly infected mice, ...
Medical research
Aug 13, 2012 |
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New advances in treating inherited retinal diseases highlighted in Human Gene Therapy
Gene therapy strategies to prevent and treat inherited diseases of the retina that can cause blindness have progressed rapidly. Positive results in animal models of human retinal disease continue to emerge, ...
Genetics
May 08, 2012 |
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Biomarker identified in relation to drug response in refractory urothelial cancer
The antiangiogenic drug pazopanib has demonstrated clinically meaningful activity in patients with refractory urothelial cancer, according to results presented at the AACR Annual Meeting 2012, held here March 31 - April 4. ...
Cancer
Apr 01, 2012 |
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Research confirms novel strategy in fight against infectious diseases
New research shows that infectious disease-fighting drugs could be designed to block a pathogen's entry into cells rather than to kill the bug itself.
Medical research
Jan 09, 2012 |
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Genetic analysis of amniotic fluid shows promise for monitoring fetal development
Researchers have demonstrated the feasibility of focused fetal gene expression analysis of target genes found in amniotic fluid using Standardized NanoArray PCR (SNAP) technology. This analysis could be used to monitor fetal ...
Genetics
Aug 08, 2011 |
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Developmental disease is recreated in an adult model
A new study published today in the journal Science has shown that the childhood disorder Rett syndrome, can be reestablished in adult animals by "switching off" a critical disease causing gene in healthy adult animals. The g ...
Diseases, Conditions, Syndromes
Jun 02, 2011 |
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Omega-3 may cut risk of artery disease, heart attacks for patients with stents
Omega-3 fatty acids, combined with two blood-thinning drugs, significantly changed the blood-clotting process and may reduce the risk of heart attacks in patients with stents in their heart arteries, according to research ...
Cardiology
May 26, 2011 |
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