News tagged with proof of concept


Research confirms novel strategy in fight against infectious diseases

New research shows that infectious disease-fighting drugs could be designed to block a pathogen's entry into cells rather than to kill the bug itself.

Medical research created Jan 09, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Antisense approach promising for treatment of parasitic infections

A targeted approach to treating toxoplasmosis, a parasitic disease, shows early promise in test-tube and animal studies, where it prevented the parasites from making selected proteins. When tested in newly infected mice, ...

Medical research created Aug 13, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Study advances use of stem cells in personalized medicine

Johns Hopkins researchers report concrete steps in the use of human stem cells to test how diseased cells respond to drugs. Their success highlights a pathway toward faster, cheaper drug development for some genetic illnesses, ...

Medical research created Nov 26, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Scientists find way to image brain waste removal process, may lead to Alzheimer's diagnostic

(Medical Xpress)—A novel way to image the entire brain's glymphatic pathway, a dynamic process that clears waste and solutes from the brain that otherwise might build-up and contribute to the development ...

Neuroscience created Feb 25, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

In lab, drug-on-the-cob fights rare disease

Biologists in Canada have made a medical enzyme using genetically-engineered corn, a feat that could one day slash the cost of treating a life-threatening inherited disease, a journal reported on Tuesday.

Diseases, Conditions, Syndromes created Sep 18, 2012 | popularity not rated yet | comments 0

HIV 'cure' in infancy, caution experts

AIDS experts cautioned Monday against hype of a cure after doctors in the United States suppressed HIV in a child born with the virus by administering a potent drug cocktail shortly after birth. ...

HIV & AIDS created Mar 04, 2013 | popularity 5 / 5 (1) | comments 0

Biomarker identified in relation to drug response in refractory urothelial cancer

The antiangiogenic drug pazopanib has demonstrated clinically meaningful activity in patients with refractory urothelial cancer, according to results presented at the AACR Annual Meeting 2012, held here March 31 - April 4. ...

Cancer created Apr 01, 2012 | popularity 5 / 5 (1) | comments 0

Genetic analysis of amniotic fluid shows promise for monitoring fetal development

Researchers have demonstrated the feasibility of focused fetal gene expression analysis of target genes found in amniotic fluid using Standardized NanoArray PCR (SNAP) technology. This analysis could be used to monitor fetal ...

Genetics created Aug 08, 2011 | popularity not rated yet | comments 0 | with audio podcast

Experimental agent briefly eases depression rapidly in test: Works in brain like ketamine, with fewer side effects

(Medical Xpress)—A drug that works through the same brain mechanism as the fast-acting antidepressant ketamine briefly improved treatment-resistant patients' depression symptoms in minutes, with minimal untoward side effects, ...

Psychology & Psychiatry created Dec 11, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

New advances in treating inherited retinal diseases highlighted in Human Gene Therapy

Gene therapy strategies to prevent and treat inherited diseases of the retina that can cause blindness have progressed rapidly. Positive results in animal models of human retinal disease continue to emerge, ...

Genetics created May 08, 2012 | popularity 5 / 5 (1) | comments 0

Morning vs nighttime replacement affects adverse events with extended-wear contact lenses

For people using 30-day extended-wear/continuous-wear (EW/CW) contact lenses, replacing lenses at night doesn't lower the risk of complications compared to changing lenses monthly, suggests a study – "The Effect of Daily ...

Ophthalmology created Dec 10, 2012 | popularity not rated yet | comments 0