News tagged with protease inhibitor


Interferon-free therapies for hep C virus look promising

(HealthDay)—For untreated patients with hepatitis C virus (HCV), treatment with an oral nucleotide inhibitor of HCV polymerase, sofosbuvir, plus ribavirin seems effective for genotypes 1, 2, and 3; and ...

Diseases, Conditions, Syndromes created Jan 03, 2013 | popularity not rated yet | comments 0

HIV treatment reduces risk of malaria recurrence in children, study shows

A combination of anti-HIV drugs has been found to also reduce the risk of recurrent malaria by nearly half among HIV-positive children, according to researchers supported by the National Institutes of Health.

Diseases, Conditions, Syndromes created Nov 28, 2012 | popularity not rated yet | comments 0 | with audio podcast

HIV drug shows efficacy in treating mouse models of HER2+ breast cancer

The HIV protease inhibitor, Nelfinavir, can be used to treat HER2-positive breast cancer in the same capacity and dosage regimen that it is used to treat HIV, according to a study published October 5 in the Journal of th ...

Cancer created Oct 06, 2012 | popularity not rated yet | comments 0 | with audio podcast

Scientists gain new insights into Taspase1 function

Scientists at the University Medical Center of Johannes Gutenberg University Mainz in Germany identified a novel strategy to target the oncologically relevant protein-cleaving enzyme Taspase1. Taspase1 levels are not only ...

Cancer created Jul 10, 2012 | popularity not rated yet | comments 0

Flower power may be answer to itchy problem

Sunflowers may hold the solution to a problem which gets under the skin of millions of Australians every year.

Medical research created Jun 25, 2012 | popularity not rated yet | comments 0

Drug interactions won't exclude HCV transplant or HIV co-infected patients from treatment

New data from a number of clinical trials presented for the first time at the International Liver Congress 2012 provides hope for previously difficult to treat hepatitis C (HCV) patient populations.

Diseases, Conditions, Syndromes created Apr 19, 2012 | popularity not rated yet | comments 0

Cholesterol levels elevated in toddlers taking anti-HIV drugs

(Medical Xpress) -- Toddlers receiving anti-HIV drugs have higher cholesterol levels, on average, than do their peers who do not have HIV, according to researchers at the National Institutes of Health and other institutions.

HIV & AIDS created Nov 22, 2011 | popularity not rated yet | comments 0 | with audio podcast

Drug designer: New tool reveals mutations that cause HIV-drug resistance

Protease inhibitor drugs are one of the major weapons in the fight against HIV, the virus that causes AIDS, but their effectiveness is limited as the virus mutates and develops resistance to the drugs over time. Now a new ...

HIV & AIDS created Jul 08, 2011 | popularity not rated yet | comments 0

Certain HIV medication associated with adrenal dysfunction in newborns of HIV-1 infected mothers

Infants of human immunodeficiency virus 1 (HIV-1) infected mothers who were treated before and after birth with the protease inhibitor lopinavir-ritonavir were more likely to experience adrenal dysfunction, including life-threatening ...

HIV & AIDS created Jul 05, 2011 | popularity not rated yet | comments 0

New drug represents breakthrough in treatment of hepatitis C

The drug telaprevir (Incivek) provides a dramatic improvement in the treatment of the most common form of hepatitis C infection, says an international team of investigators led by Dr. Ira M. Jacobson of NewYork-Presbyterian ...

Medications created Jun 22, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Potential new drug candidate found for Alzheimer's disease

Researchers at the University of California, San Diego, the Medical University of South Carolina and American Life Science Pharmaceuticals of San Diego have demonstrated that oral administration of a cysteine protease inhibitor, ...

Diseases, Conditions, Syndromes created May 31, 2011 | popularity 5 / 5 (5) | comments 0 | with audio podcast

One drug, many targets: Finding molecular targets of an HIV drug used in cancer therapy

Researchers at the University of California, San Diego and Hunter College of the City University of New York (CUNY) have identified potential human molecular targets of the anti-HIV drug Nelfinavir, which may explain why ...

Medications created Apr 28, 2011 | popularity 5 / 5 (1) | comments 0 | with audio podcast