Researchers have published the first highly detailed description of how neurotensin, a neuropeptide hormone which modulates nerve cell activity in the brain, interacts with its receptor. Their results suggest that neuropeptide ...
Oct 10, 2012
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Scientists have revealed details of the discovery of new inhibitors of the BCL6 protein, which is involved in driving several cancer types including the blood cancer B-cell lymphoma.
Feb 9, 2023
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Scientists at The University of Manchester have developed a more efficient method to produce medicines that are in development for the treatment of COVID-19, cancer and other diseases that affect many of the world's population.
May 20, 2021
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American and Polish scientists, reporting Oct. 16 in the journal Science Advances, laid out a novel rationale for COVID-19 drug design—blocking a molecular "scissor" that the virus uses for virus production and to disable ...
Oct 16, 2020
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Researchers at Cardiff University have used X-ray crystallography and computer simulation to get a closer look at how viruses bind cells and cause infection.
Feb 19, 2019
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The molecular structure of the Zika virus as seen on x-ray crystallography revealed electrostatic differences in a key protein compared with other flaviviruses that might explain how it infects human cells, according to a ...
Apr 19, 2016
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Researchers at Karolinska Institutet have obtained the first 3D structure of uromodulin, the building block of the unique safety net that constantly protects our urinary tract against bacterial infections. Uromodulin also ...
Jan 27, 2016
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A flu virus acts like a Trojan horse as it attacks and infects host cells. Scientists at Rice University and Baylor College of Medicine have acquired a clearer view of the well-hidden mechanism involved.
Aug 1, 2014
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(Medical Xpress)—An experiment just launched into orbit by a team of Caltech researchers could be an important step toward understanding a devastating neurodegenerative disease.
Apr 21, 2014
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Scientists working to design advanced medicines that are perfectly targeted to control the body's natural receptors have made a major discovery using Diamond's Microfocus Macromolecular Crystallography beamline (I24). For ...
Jul 18, 2013
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