News tagged with protein degradation
Cytoskeletal dysregulation underlies Buruli ulcer formation
Mycobacterium ulcerans infects the skin and subcutaneous tissues and secretes a lipid toxin, mycolactone, which causes open skin lesions, known as Buruli ulcers.
Medical research
Mar 15, 2013 |
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Cell metabolism: Muscle loss can be caused by mitochondrial degradation induced by protein Mul1
Muscle withering can occur as part of the progression of many diseases, including cancer and muscular dystrophy, as well as during the normal aging process. Cellular organelles known as mitochondria provide ...
Medical research
Mar 13, 2013 |
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Rare, lethal childhood disease tracked to failure to degrade nerve cells' filaments
For the first time, a defective protein that plays a specific role in degrading intermediate filaments (IF), one of three classes of filaments that form the structure of nerve cells, has been discovered by an international ...
Medical research
Dec 17, 2012 |
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Research may have important implications for combating diabetes
(Medical Xpress)—Research by University of Notre Dame biochemist Anthony S. Serianni is providing new insights that could have important implications for understanding and treating diabetes.
Diabetes
Dec 11, 2012 |
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Impaired protein degradation causes muscle diseases
New insights into certain muscle diseases, the filaminopathies, are reported by an international research team led by Dr. Rudolf Andre Kley of the RUB's University Hospital Bergmannsheil in the journal Brain. The scientists from t ...
Medical research
Sep 25, 2012 |
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Japanese researchers show that acupuncture can improve skeletal muscle atrophy
A team of Japanese researchers will reveal study results Monday at the Experimental Biology 2012 meeting that show how acupuncture therapy mitigates skeletal muscle loss and holds promise for those seeking improved mobility ...
Medical research
Apr 23, 2012 |
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ISG15: A novel therapeutic target to slow breast cancer cell motility
Interferon-stimulated gene 15 (ISG15), a ubiquitin like protein, is highly elevated in a variety of cancers including breast cancer. How the elevated ISG15 pathway contributes to tumorigenic phenotypes remains unclear and ...
Cancer
Jan 11, 2012 |
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BGI reports study results on frequent mutation of genes encoding UMPP components in kidney cancer
BGI, the world's largest genomics organization, announced that a study on frequent mutation of genes encoding ubiquitin-mediated proteolysis pathway (UMPP) components in clear cell renal cell carcinoma (ccRCC) is published ...
Cancer
Dec 04, 2011 |
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